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3.5.4.5: cytidine deaminase

This is an abbreviated version!
For detailed information about cytidine deaminase, go to the full flat file.

Word Map on EC 3.5.4.5

Reaction

2'-deoxycytidine
+
H2O
=
2'-deoxyuridine
+
NH3

Synonyms

activation-induced cytidine deaminase, AICDA, canine hepatic cyd deaminase, CDA, CDABcald, CDABpsy, CDABsub, CDase, CDD, CR deaminase, cyd deaminase, Cytidine aminohydrolase, cytidine deaminase, cytidine/2'-deoxycytidine aminohydrolase, cytosine nucleoside deaminase, DCD, dCDA, deoxycytidine deaminase, EC 3.5.4.14, mammalian deminase, T-CDA, yeast cytidine deaminase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.5 cytidine deaminase

pH Stability

pH Stability on EC 3.5.4.5 - cytidine deaminase

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pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3 - 10.5
-
deoxycytidine as substrate, beyond these extremes rapid inactivation
209668
3.5 - 10.5
-
deoxycytidine as substrate, beyond these extremes rapid inactivation
209661
5.5 - 9.5
-
stable for some hours at 4°C, rapid inactivation and precipitation of the enzyme occurs at pH lower 5
209492
6 - 9
-
reasonably stable in this range
209660
6.5 - 10.7
-
irreversible loss of activity at pH values below 4
209648