3.5.4.5: cytidine deaminase
This is an abbreviated version!
For detailed information about cytidine deaminase, go to the full flat file.
Word Map on EC 3.5.4.5
-
3.5.4.5
-
hypermutation
-
immunoglobulin
-
deamination
-
ige
-
b-cells
-
lymphocyte
-
leukemia
-
lymphoma
-
diversification
-
class-switched
-
apobec3g
-
immunodeficiency
-
deaminases
-
uracil
-
gemcitabine
-
single-stranded
-
uridine
-
isotype
-
virion
-
arabinoside
-
cytarabine
-
retroviruses
-
ssdna
-
glycosylase
-
lymphomagenesis
-
deoxyuridine
-
cd40l
-
encapsidation
-
1-beta-d-arabinofuranosylcytosine
-
deoxycytidylate
-
c-to-u
-
blimp-1
-
nickase
-
mrna-editing
-
capecitabine
-
polypeptide-like
-
uracil-dna
-
microhomology
-
abasic
-
medicine
-
5-aza-cdr
-
drug development
-
protospacer
-
diagnostics
-
5'-deoxy-5-fluorouridine
-
5\'-dfur
-
plasmablast
-
retroelements
-
zebularine
-
ara-ctp
-
t-independent
-
anti-cd40
-
unmutated
- 3.5.4.5
-
hypermutation
- immunoglobulin
-
deamination
- ige
- b-cells
- lymphocyte
- leukemia
- lymphoma
-
diversification
-
class-switched
- apobec3g
- immunodeficiency
- deaminases
- uracil
- gemcitabine
-
single-stranded
- uridine
-
isotype
- virion
- arabinoside
- cytarabine
- retroviruses
- ssdna
- glycosylase
-
lymphomagenesis
- deoxyuridine
- cd40l
-
encapsidation
- 1-beta-d-arabinofuranosylcytosine
- deoxycytidylate
-
c-to-u
-
blimp-1
-
nickase
-
mrna-editing
- capecitabine
-
polypeptide-like
-
uracil-dna
-
microhomology
-
abasic
- medicine
-
5-aza-cdr
- drug development
-
protospacer
- diagnostics
- 5'-deoxy-5-fluorouridine
-
5\'-dfur
-
plasmablast
-
retroelements
- zebularine
- ara-ctp
-
t-independent
-
anti-cd40
-
unmutated
Reaction
Synonyms
activation-induced cytidine deaminase, AICDA, canine hepatic cyd deaminase, CDA, CDABcald, CDABpsy, CDABsub, CDase, CDD, CR deaminase, cyd deaminase, Cytidine aminohydrolase, cytidine deaminase, cytidine/2'-deoxycytidine aminohydrolase, cytosine nucleoside deaminase, DCD, dCDA, deoxycytidine deaminase, EC 3.5.4.14, mammalian deminase, T-CDA, yeast cytidine deaminase
ECTree
Advanced search results
Temperature Stability
Temperature Stability on EC 3.5.4.5 - cytidine deaminase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
100
15 - 75
-
wild-type enzyme and mutant R68Q are stable, while the stability of mutant Y60G is decreased above 65°C
50
60
-
relatively labile to thermal treatment, complete inactivation by incubation for 30 min
70 - 90
72
-
relatively heat stable, no loss of activity when heated for 15 min, activity completely lost after heating at 75°C
-
the CDA activity of genes SH1067 and SH1077 remains constant for 3 h at 70°C, the half-time of residual activities of SH1067 and SH1077 increases up to 200% as compared with that of gene T53 at 80°C, SH1067 shows over 200% increased half-time than that of T53, although 120 min later, no activity remains at 90°C. SH2426 shows 150% increased half-time than that of T53 at 70°C. SH2429 shows over 50-70% decreased thermostability than that of T53 at 70°C, residual activity disappears after 10 min at over 80°C
70 - 90
-
the CDA activity of genes SH1067 and SH1077 remains constant for 3 h at 70°C, the half-time of residual activities of SH1067 and SH1077 increases up to 200% as compared with that of gene T53 at 80°C, SH1067 shows over 200% increased half-time than that of T53, although 120 min later, no activity remains at 90°C. SH2426 shows 150% increased half-time than that of T53 at 70°C. SH2429 shows over 50-70% decreased thermostability than that of T53 at 70°C, residual activity disappears after 10 min at over 80°C