3.5.4.41: 5'-deoxyadenosine deaminase

This is an abbreviated version!
For detailed information about 5'-deoxyadenosine deaminase, go to the full flat file.

Reaction

Synonyms

DadD, MJ1541

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.4 In cyclic amidines

                3.5.4.41 5'-deoxyadenosine deaminase

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Results	in table
1	Activating Compound
402	AA Sequence
1	Cloned(Commentary)
1	General Information
4	kcat/KM [mM/s]
4	KM Value [mM]
4	Metals/Ions
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
2	Organism
4	Protein Variants
1	Purification (Commentary)
1	Reaction
2	Reference
2	Substrates and Products (Substrate)
2	Subunits
2	Synonyms
1	Systematic Name
3	Temperature Stability [°C]
4	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 3.5.4.41 - 5'-deoxyadenosine deaminase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

5'-deoxyadenosine + H2O

5'-deoxyinosine + NH3

2 entries

5'-deoxyadenosine + H2O

5'-deoxyinosine + NH3

Methanocaldococcus jannaschii

Q58936

the enzyme is involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens

727779

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-

?

5'-deoxyadenosine + H2O

5'-deoxyinosine + NH3

Methanocaldococcus jannaschii

Q58936

catalytic efficiency of the enzyme for 5'-deoxyadenosine is 1000fold higher than for S-methyl-5'-thioadenosine, and 10000fold higher than with S-adenosyl-L-homocysteine or adenosine

727779

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-

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