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3.5.4.38: single-stranded DNA cytosine deaminase

This is an abbreviated version!
For detailed information about single-stranded DNA cytosine deaminase, go to the full flat file.

Word Map on EC 3.5.4.38

Reaction

cytosine in single-stranded DNA
+
H2O
=
uracil in single-stranded DNA
+
NH3

Synonyms

A3F, activation-induced cytidine deaminase, activation-induced deaminase, AICDA, AID, APOBEC3A, APOBEC3B, APOBEC3C, APOBEC3D, APOBEC3F, APOBEC3G, APOBEC3H, APOBEC3Z1, CDA1, single-stranded (ss)DNA deoxycytidine deaminase, ssDNA cytidine deaminase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.38 single-stranded DNA cytosine deaminase

Metals Ions

Metals Ions on EC 3.5.4.38 - single-stranded DNA cytosine deaminase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Zinc
coordination of a secondary zinc ion enhances deamination activity up to 160%ing is pinpointed to loop-3 which harbors a catalytically essential and spatially conserved asparagine at its N-terminus
additional information
the enzyme requires a tightly bound metal ion for its action