3.5.4.32: 8-oxoguanine deaminase
This is an abbreviated version!
For detailed information about 8-oxoguanine deaminase, go to the full flat file.
Reaction
Synonyms
8-OGD, 8-oxoGD, Pa0142
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Natural Substrates Products on EC 3.5.4.32 - 8-oxoguanine deaminase
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REACTION DIAGRAM
8-oxoguanine + H2O
8-oxoxanthine + NH3
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8-oxoguanine (8-oxoG), which is formed by the oxidation of guanine within DNA via reactive oxygen species. If uncorrected, this modification leads to the incorporation of 8-oxoG:A mismatches and eventually to G:C to T:A transversions
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?
8-oxoguanine + H2O
urate + NH3
8-oxoguanine (8-oxoG), which is formed by the oxidation of guanine within DNA via reactive oxygen species. If uncorrected, this modification leads to the incorporation of 8-oxoG:A mismatches and eventually to G:C to T:A transversions
-
-
?