3.5.4.31: S-methyl-5'-thioadenosine deaminase

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For detailed information about S-methyl-5'-thioadenosine deaminase, go to the full flat file.

Reaction

Synonyms

5-methylthioadenosine deaminase, 5-methylthioadenosine/S-adenosylhomocysteine deaminase, DadD, MJ1541, MTA deaminase, MtaD, MTADA, PA3170, Tm0936

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.4 In cyclic amidines

3.5.4.31 S-methyl-5'-thioadenosine deaminase

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Results	in table
1	Activating Compound
6980	AA Sequence
4	Cloned(Commentary)
2	Crystallization (Commentary)
2	General Information
1	IC50 Value
7	Inhibitors
15	kcat/KM [mM/s]
6	Ki Value [mM]
15	KM Value [mM]
5	Metals/Ions
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
4	Organism
3	Pathway
2	PDB ID
1	pH Optimum
7	Protein Variants
3	Purification (Commentary)
1	Reaction
4	Reference
11	Substrates and Products (Substrate)
2	Subunits
14	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
4	Temperature Stability [°C]
15	Turnover Number [1/s]

Crystallization

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Crystallization on EC 3.5.4.31 - S-methyl-5'-thioadenosine deaminase

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in complex with 5'-methylthiocoformycin, hanging or sitting drop vapor diffusion method, using 1.26 M sodium phosphate (monobasic) and 0.14 M potassium phosphate (dibasic) at a final pH of 5.6 at 18°C

Pseudomonas aeruginosa

Q9HZ64

733337

X-ray crystal structure of the complex between Tm0936 and the product resulting from the deamination of SAH, S-inosylhomocysteine

Thermotoga maritima

Q9X034

713096