3.5.4.30: dCTP deaminase (dUMP-forming)
This is an abbreviated version!
For detailed information about dCTP deaminase (dUMP-forming), go to the full flat file.
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Synonyms
DCD-DUT, DCD:DUT, dcdB, DCDDUT, dCTP deaminase-dUTP pyrophosphatase, dCTP deaminase-dUTPase, MJ0430
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Systematic Name
Systematic Name on EC 3.5.4.30 - dCTP deaminase (dUMP-forming)
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dCTP aminohydrolase (dUMP-forming)
Requires Mg2+. Is highly specific for dCTP as substrate as dCMP, CTP, CDP, CMP, cytosine or deoxycytosine are not deaminated. While most bacteria require two enzymes to form dUMP from dCTP (EC 3.5.4.13, dCTP deaminase and EC 3.6.1.23, dUTP diphosphatase), the archaeon Methanocaldococcus jannaschii uses a single enzyme to carry out both functions. This enzyme can also act as a dUTP diphosphatase, but more slowly.