3.5.4.3: guanine deaminase

This is an abbreviated version!
For detailed information about guanine deaminase, go to the full flat file.

Word Map on EC 3.5.4.3

3.5.4.3

xanthine

purine

deamination

uric

agdas

hypoxanthine

anogenital

8-azaguanine

anus

penis

scrotum

medicine

cephalad

deaminases

drug development

analysis

food industry

Reaction

Synonyms

Agdap, cypin, cytosolic PSD-95 interactor, E. coli guanine deaminase, GAH, GDA, GDEase, GUA, guaD, guanase, guanine aminase, Guanine aminohydrolase, guanine deaminase, GUD1, human guanine deaminase, KLLAOD9492, More, NE0047, p51-nedasin, YgfP

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.4 In cyclic amidines

3.5.4.3 guanine deaminase

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Results	in table
11	Activating Compound
13922	AA Sequence
13	Application
1	CAS Registry Number
12	Cloned(Commentary)
5	Crystallization (Commentary)
274	Disease/ Diagnostics
3	Expression
13	General Information
4	General Stability
141	Inhibitors
13	kcat/KM [mM/s]
26	Ki Value [mM]
106	KM Value [mM]
14	Localization
26	Metals/Ions
122	Molecular Weight [Da]
72	Natural Substrates/ Products (Substrates)
340	Organism
9	Pathway
21	PDB ID
59	pH Optimum
7	pH Range
2	pH Stability
2	pI Value
18	Protein Variants
32	Purification (Commentary)
3	Reaction
2	Reaction Type
98	Reference
151	Source Tissue
32	Specific Activity [micromol/min/mg]
13	Storage Stability
172	Substrates and Products (Substrate)
61	Subunits
48	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Range [°C]
26	Temperature Stability [°C]
14	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 3.5.4.3 - guanine deaminase

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Blastobotrys adeninivorans

the native enzyme remains stable for 1 h at up to 30°C

734510

2 entries

Homo sapiens

relatively stable, incubation for 5 min, 3% loss in activity, 17% after 30 min

activity completely lost after 30 min incubation

209585, 209586

Rattus norvegicus

activity remains unaffected from 0-50°C, 19.3% inactivation at 60°C, 33% inactivation at 70°C, complete lost of activity at 80°C

209588