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3.5.4.3: guanine deaminase

This is an abbreviated version!
For detailed information about guanine deaminase, go to the full flat file.

Word Map on EC 3.5.4.3

Reaction

guanine
+
H2O
=
xanthine
 +
NH3

Synonyms

Agdap, cypin, cytosolic PSD-95 interactor, E. coli guanine deaminase, GAH, GDA, GDEase, GUA, guaD, guanase, guanine aminase, Guanine aminohydrolase, guanine deaminase, GUD1, human guanine deaminase, KLLAOD9492, More, NE0047, p51-nedasin, YgfP

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.3 guanine deaminase

KI Value

KI Value on EC 3.5.4.3 - guanine deaminase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.129
(6R)-6-hydroxy-3-beta-D-ribofuranosyl-3a,4,5,6,7,8a-hexahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.119
(6S)-6-hydroxy-3-beta-D-ribofuranosyl-3a,4,5,6,7,8a-hexahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.0438
1-(4-methoxybenzyl)-4-benzyl-5-ethoxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8-(1H)-one
-
at 25°C and pH 7.4
0.0265
1-(4-methoxybenzyl)-4-benzyl-5-methoxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(1H)-one
-
at 25°C and pH 7.4
0.00188
2,6-diaminopurine
-
in 25 mM Tris-HCl, 137 mM NaCl, 2.7 mM KCl, at pH 7.4 and 25°C
0.0397
3-(4-fluorobenzyl)-5-methoxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.0334
3-(4-methoxybenzyl)-5-ethoxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.021
3-benzyl-5-butoxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.054
3-benzyl-5-ethoxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.04
3-benzyl-5-hydroxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.047
3-benzyl-5-methoxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.00201 - 0.02
3-benzyl-6-(hydroxymethyl)-3,4,6,7-tetrahydroimidazo[4,5-e][1,4]diazepine-5,8-dione
0.0088
4-benzyl-5-methoxy-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(3H)-one
-
at 25°C and pH 7.4
0.00444
5-amino-4-imidazole carboxamide
-
in 25 mM Tris-HCl, 137 mM NaCl, 2.7 mM KCl, at pH 7.4 and 25°C
0.0475
5-methoxy-1-(4-methoxybenzyl)-4,5,6,7-tetrahydroimidazo[4,5-e][1,4]diazepin-8(1H)-one
-
at 25°C and pH 7.4
0.00536 - 0.054
6-(hydroxymethyl)-3,4,6,7-tetrahydroimidazo[4,5-e][1,4]diazepine-5,8-dione
0.0005
6-hydroxy-3,4,6,7-tetrahydroimidazo[4,5-e][1,4]diazepine-5,8-dione
-
pH 7.4, 25°C
0.00555
7-methylguanine
-
in 25 mM Tris-HCl, 137 mM NaCl, 2.7 mM KCl, at pH 7.4 and 25°C
0.0025 - 2.5
azepinomycin
0.0102
Caffeine
-
in 25 mM Tris-HCl, 137 mM NaCl, 2.7 mM KCl, at pH 7.4 and 25°C
0.00344
N-2-acetylguanine
-
in 25 mM Tris-HCl, 137 mM NaCl, 2.7 mM KCl, at pH 7.4 and 25°C
0.00434
uric acid
-
in 25 mM Tris-HCl, 137 mM NaCl, 2.7 mM KCl, at pH 7.4 and 25°C
0.00196
xanthine
-
in 25 mM Tris-HCl, 137 mM NaCl, 2.7 mM KCl, at pH 7.4 and 25°C