3.5.4.3: guanine deaminase

This is an abbreviated version!
For detailed information about guanine deaminase, go to the full flat file.

Word Map on EC 3.5.4.3

3.5.4.3

xanthine

purine

deamination

uric

agdas

hypoxanthine

anogenital

8-azaguanine

anus

penis

scrotum

medicine

cephalad

deaminases

drug development

analysis

food industry

Reaction

Synonyms

Agdap, cypin, cytosolic PSD-95 interactor, E. coli guanine deaminase, GAH, GDA, GDEase, GUA, guaD, guanase, guanine aminase, Guanine aminohydrolase, guanine deaminase, GUD1, human guanine deaminase, KLLAOD9492, More, NE0047, p51-nedasin, YgfP

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.4 In cyclic amidines

3.5.4.3 guanine deaminase

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Results	in table
11	Activating Compound
13922	AA Sequence
13	Application
1	CAS Registry Number
12	Cloned(Commentary)
5	Crystallization (Commentary)
274	Disease/ Diagnostics
3	Expression
13	General Information
4	General Stability
141	Inhibitors
13	kcat/KM [mM/s]
26	Ki Value [mM]
106	KM Value [mM]
14	Localization
26	Metals/Ions
122	Molecular Weight [Da]
72	Natural Substrates/ Products (Substrates)
340	Organism
9	Pathway
21	PDB ID
59	pH Optimum
7	pH Range
2	pH Stability
2	pI Value
18	Protein Variants
32	Purification (Commentary)
3	Reaction
2	Reaction Type
98	Reference
151	Source Tissue
32	Specific Activity [micromol/min/mg]
13	Storage Stability
172	Substrates and Products (Substrate)
61	Subunits
48	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Range [°C]
26	Temperature Stability [°C]
14	Turnover Number [1/s]

Cloned

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Cloned on EC 3.5.4.3 - guanine deaminase

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3 entries

cloned from kidney and brain cDNA libraries, PCR, subcloned into bacterial expression vector pMAL-c2, expressed in mice DH5-alpha cells and purified

Homo sapiens

Q9Y2T3

209602

expressed in Arxula adeninivorans strain G1212

Blastobotrys adeninivorans

734510

expressed in Escherichia BL21(DE3) pLysS cells

Bradyrhizobium japonicum

712293

expressed in Escherichia coli BL21 cells

Drosophila melanogaster

712380

expression in Escherichia coli

3 entries

expression of wild-type and mutant enzymes in COS-7 cells, subcloning in Escherichia coli strain DH5alpha

Rattus norvegicus

689944

gene identified with human cDNA, amplified, subcloned into pMAL-c2 vector, expressed and purified

Escherichia coli

209603