3.5.4.3: guanine deaminase
This is an abbreviated version!
For detailed information about guanine deaminase, go to the full flat file.
Word Map on EC 3.5.4.3
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3.5.4.3
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xanthine
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purine
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deamination
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uric
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agdas
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hypoxanthine
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anogenital
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8-azaguanine
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anus
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penis
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scrotum
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medicine
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cephalad
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deaminases
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drug development
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analysis
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food industry
- 3.5.4.3
- xanthine
- purine
-
deamination
-
uric
-
agdas
- hypoxanthine
-
anogenital
- 8-azaguanine
-
anus
-
penis
-
scrotum
- medicine
-
cephalad
- deaminases
- drug development
- analysis
- food industry
Reaction
Synonyms
Agdap, cypin, cytosolic PSD-95 interactor, E. coli guanine deaminase, GAH, GDA, GDEase, GUA, guaD, guanase, guanine aminase, Guanine aminohydrolase, guanine deaminase, GUD1, human guanine deaminase, KLLAOD9492, More, NE0047, p51-nedasin, YgfP
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Application
Application on EC 3.5.4.3 - guanine deaminase
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analysis
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colorimetric and HPLC assay method using guanosine as a prosubstrate. Method is suitable for routine assays for measuring plasma enzyme over a wide range of activites
drug development
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because these enzymes play an important role in nucleotide metabolism, they are relevant targets in anticancer and antibacterial therapies
food industry
medicine
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in beer samples treated with adenine deaminase and guanine deaminase, the adenine concentration in beer drops 66-67% and guanine concentration in beer drops from 68.8 microM to a minimal amount
food industry
Kluyveromyces lactis MTCC 458
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in beer samples treated with adenine deaminase and guanine deaminase, the adenine concentration in beer drops 66-67% and guanine concentration in beer drops from 68.8 microM to a minimal amount
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enzyme has been implicated in cancer, liver disease, saturine gout, psoriasis and autoimmune disease, histochemical method for demonstration of guanase should be useful clinically, guanase activity increases significantly in lung and gastric cancer tissues or in patients with liver diseases like hepatitis, guanase is a biochemical indicator of rejection in liver transplant recipients, serum enzyme activity is the most sensitive indicator of liver disease, inhibition of guanase has beneficial implications in cancer chemotherapy, an inhibitor as chemotherapeutic agent selectively inhibit the growth of rapidly proliferating cancerous cells via depletion of the purine nucleotide pool
medicine
enzyme has been implicated in cancer, liver disease, saturine gout, psoriasis and autoimmune disease, histochemical method for demonstration of guanase should be useful clinically, guanase activity increases significantly in lung and gastric cancer tissues or in patients with liver diseases like hepatitis, guanase is a biochemical indicator of rejection in liver transplant recipients, serum enzyme activity is the most sensitive indicator of liver disease, inhibition of guanase has beneficial implications in cancer chemotherapy, an inhibitor as chemotherapeutic agent selectively inhibit the growth of rapidly proliferating cancerous cells via depletion of the purine nucleotide pool
medicine
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test for cancerous tissues, lower guanase activities compared with non-cancerous ones
medicine
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colorimetric and HPLC assay method using guanosine as a prosubstrate. Method is suitable for routine assays for measuring plasma enzyme over a wide range of activites
medicine
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GDA is an attractive and potential drug target for treatment of both liver diseases and cognitive disorders
medicine
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GDA is an attractive and potential drug target for treatment of both liver diseases and cognitive disorders
medicine
GDA is an attractive and potential drug target for treatment of both liver diseases and cognitive disorders