3.5.4.29: GTP cyclohydrolase IIa
This is an abbreviated version!
For detailed information about GTP cyclohydrolase IIa, go to the full flat file.
Reaction
Synonyms
GCH III, GTP cyclohydrolase III, MJ0145
ECTree
3.5.4.29 GTP cyclohydrolase IIaAdvanced search results
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results (Inhibitors
Inhibitors on EC 3.5.4.29 - GTP cyclohydrolase IIa
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
8-azido-GTP
0.6 mM, 91% inhibition of GTP cyclohydrolase activity, 0.3 mM, 53% inhibition of diphosphate phosphohydrolase activity
8-bromo-GTP
0.1 mM, 50% inhibition of GTP cyclohydrolase activity, 0.1 mM, 64% inhibition of diphosphate phosphohydrolase activity
alpha,beta-methylene-GTP
0.06 mM, 80% inhibition of GTP cyclohydrolase activity, 0.6 mM, 33% inhibition of diphosphate phosphohydrolase activity
beta,gamma-methylene-GTP
0.6 mM, 34% inhibition of GTP cyclohydrolase activity
diphosphate
inhibition of diphosphate phosphohydrolase activity at high concentrations
GDP
more than 40% inhibition of GTP cyclohydrolase activity
GMP
more than 40% inhibition of GTP cyclohydrolase activity
GTP-gamma-S
0.6 mM, 80% inhibition of GTP cyclohydrolase activity
IMP
0.6 mM, 25% inhibition of GTP cyclohydrolase activity
methylene diphosphate
0.6 mM, 40% inhibition of GTP cyclohydrolase activity, 0.6 mM, 56% inhibition of diphosphate phosphohydrolase activity
NaF
0.06 mM, 55% inhibition of diphosphate phosphohydrolase activity
phosphate
0.6 mM, 25% inhibition of GTP cyclohydrolase activity
tripolyphosphate
0.6 mM, 50% inhibition of GTP cyclohydrolase activity, 0.05 mM, 52% inhibition of diphosphate phosphohydrolase activity
XTP
0.6 mM, 52% inhibition of GTP cyclohydrolase activity
