3.5.4.25: GTP cyclohydrolase II

This is an abbreviated version, for detailed information about GTP cyclohydrolase II, go to the full flat file.

Reaction

GTP
+ 3 H2O =
formate
+
2,5-diamino-6-hydroxy-4-(5-phospho-D-ribosylamino)pyrimidine
+
diphosphate

Synonyms

3,4-dihydroxy-2-butanone 4-phosphate synthase, GCH II, GCH II/III, GCH-II, GCHII, GTP cyclohydrolase II, GTP cyclohydrolase-II, GTP-8-formylhydrolase, GTPCH II, GTPCH-II, guanosine triphosphate cyclohydrolase II, guanosine triphosphate cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase, guanosine-5'-triphosphate cyclohydrolase-II, More, NbRibA, RibA, ribA2, RIBIV

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.25 GTP cyclohydrolase II