3.5.4.2: adenine deaminase

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For detailed information about adenine deaminase, go to the full flat file.

Word Map on EC 3.5.4.2

3.5.4.2

purine

hypoxanthine

inosine

nucleosidase

2.4.2.7

2\'-deoxycoformycin

deaminases

nickase

phosphoribosyltransferases

guanase

food industry

Reaction

Synonyms

aadA, AAH, Aah1p, AAur1117, ADA, ADase, ADE, adenase, adenine aminase, adenine deaminase, KLLAOE2317, MJ1459, NadA, Pa0148, Sgx9403e, Sgx9403g

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.4 In cyclic amidines

3.5.4.2 adenine deaminase

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Results	in table
23326	AA Sequence
2	Application
1	CAS Registry Number
11	Cloned(Commentary)
1	Cofactor
5	Crystallization (Commentary)
23	Disease/ Diagnostics
1	Expression
1	General Information
4	General Stability
43	Inhibitors
52	kcat/KM [mM/s]
3	Ki Value [mM]
68	KM Value [mM]
9	Localization
12	Metals/Ions
13	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
69	Organism
5	Pathway
7	PDB ID
23	pH Optimum
5	pH Range
3	pH Stability
30	Protein Variants
10	Purification (Commentary)
1	Reaction
1	Reaction Type
41	Reference
17	Specific Activity [micromol/min/mg]
8	Storage Stability
126	Substrates and Products (Substrate)
9	Subunits
23	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
2	Temperature Range [°C]
13	Temperature Stability [°C]
54	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.5.4.2 - adenine deaminase

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0.012

Leishmania braziliensis

172172

0.014 - 0.14

Saccharomyces cerevisiae

172179

0.071

Crithidia fasciculata

in crude extracts

172173

0.22

Leishmania mexicana

172172

0.58

Leishmania tarentolae

172172

0.64

Leishmania donovani

172172

0.71

Crithidia fasciculata

172172

1.4

Methanocaldococcus jannaschii

no addition of divalent cation, pH 7.0, temperature not specified in the publication

755347

1.88

Blastobotrys adeninivorans

L8BT48

after 5.26fold purification, at pH 7.4 and 40°C

734047

3.8

Azotobacter vinelandii

172177

5.3

Methanocaldococcus jannaschii

presence of Fe2+, pH 7.0, temperature not specified in the publication

755347

5.8

Methanocaldococcus jannaschii

presence of Mn2+, pH 7.0, temperature not specified in the publication

755347

5.97

Escherichia coli

pH 7.5, 37°C

650622

8.34

Saccharomyces cerevisiae

P53909

recombinant protein, adenine as substrate, 0.067 mM in 0.2 M phosphate buffer, 33°C, pH 7.0, adenine most favoured substrate, also hydrolyzes N6-substituted adenines from the cytokinin group of plant hormones, reaction products identified by mass spectroscopy, relative reaction rates given

696861

additional information

6 entries