3.5.4.2: adenine deaminase
This is an abbreviated version!
For detailed information about adenine deaminase, go to the full flat file.
Word Map on EC 3.5.4.2
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3.5.4.2
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purine
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hypoxanthine
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inosine
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nucleosidase
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2.4.2.7
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2\'-deoxycoformycin
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deaminases
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nickase
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phosphoribosyltransferases
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guanase
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food industry
- 3.5.4.2
- purine
- hypoxanthine
- inosine
- nucleosidase
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2.4.2.7
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2\'-deoxycoformycin
- deaminases
-
nickase
-
phosphoribosyltransferases
- guanase
- food industry
Reaction
Synonyms
aadA, AAH, Aah1p, AAur1117, ADA, ADase, ADE, adenase, adenine aminase, adenine deaminase, KLLAOE2317, MJ1459, NadA, Pa0148, Sgx9403e, Sgx9403g
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Natural Substrates Products
Natural Substrates Products on EC 3.5.4.2 - adenine deaminase
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REACTION DIAGRAM
N6-(2-isopentenyl)adenine + H2O
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partial conversion, at endo-side of N6 amino groups, release of N6-side chain amines
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-
?
N6-(2-isopentenyl)adenine + H2O
hypoxanthine + 3-methylbut-2-en-1-amine
partial conversion, at endo-side of N6 amino groups, release of N6-side chain amines
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-
?
adenine + H2O
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purine salvage pathway and nitrogen metabolism
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-
?
adenine + H2O
hypoxanthine + NH3
irreversible deamination, metabolic salvage pathway of purines
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ir
adenine + H2O
hypoxanthine + NH3
irreversible deamination, metabolic salvage pathway of purines
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ir
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release of hypoxanthine and inosine, release of amine from from the cytokinine side chain
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-
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kinetin + H2O
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release of hypoxanthine and inosine, release of amine from from the cytokinine side chain
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-
?
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gene AAH1 is tightly downregulated upon cell entry into the non-proliferating state/quiescence, which is induced by nutrient limitations, the Srb10p cyclin-dependent kinase and its cyclin, Srb11p, regulate AAH1 expression at the transcriptional level, while Saf1p, a previously uncharacterized F-box protein, acts at a post-transcriptional level by promoting degradation of Aah1p, Aah1p expression is controlled by the RAS cAMP pathway, overview
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additional information
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gene AAH1 is tightly downregulated upon cell entry into the non-proliferating state/quiescence, which is induced by nutrient limitations, the Srb10p cyclin-dependent kinase and its cyclin, Srb11p, regulate AAH1 expression at the transcriptional level, while Saf1p, a previously uncharacterized F-box protein, acts at a post-transcriptional level by promoting degradation of Aah1p, Aah1p expression is controlled by the RAS cAMP pathway, overview
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?