3.5.4.2: adenine deaminase

This is an abbreviated version!
For detailed information about adenine deaminase, go to the full flat file.

Reaction

Synonyms

aadA, AAH, Aah1p, AAur1117, ADA, ADase, ADE, adenase, adenine aminase, adenine deaminase, KLLAOE2317, MJ1459, NadA, Pa0148, Sgx9403e, Sgx9403g

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.4 In cyclic amidines

                3.5.4.2 adenine deaminase

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Results	in table
23326	AA Sequence
2	Application
1	CAS Registry Number
11	Cloned(Commentary)
1	Cofactor
5	Crystallization (Commentary)
23	Disease/ Diagnostics
1	Expression
1	General Information
4	General Stability
43	Inhibitors
52	kcat/KM [mM/s]
3	Ki Value [mM]
68	KM Value [mM]
9	Localization
12	Metals/Ions
13	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
69	Organism
5	Pathway
7	PDB ID
23	pH Optimum
5	pH Range
3	pH Stability
30	Protein Variants
10	Purification (Commentary)
1	Reaction
1	Reaction Type
41	Reference
17	Specific Activity [micromol/min/mg]
8	Storage Stability
126	Substrates and Products (Substrate)
9	Subunits
23	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
2	Temperature Range [°C]
13	Temperature Stability [°C]
54	Turnover Number [1/s]

Disease

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Disease on EC 3.5.4.2 - adenine deaminase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

adenine deaminase deficiency

Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency.

23028826

Hematologic Diseases

[Adenase of formed elements of blood of donors and of patients with different blood diseases]

1071848

Infections

Effects of iron supplementation on blood adenine deaminase activity and oxidative stress in Trypanosoma evansi infection of rats.

25300765

Neuroblastoma

Adenosine transport by a variant of C1300 murine neuroblastoma cells deficient in adenosine kinase.

6246950

purine-nucleoside phosphorylase deficiency

Cross correction following haemopoietic stem cell transplant for purine nucleoside phosphorylase deficiency: engrafted donor-derived white blood cells provide enzyme to residual enzyme-deficient recipient cells.

23430937

Tuberculosis

Eleven years of experience with dialysis associated tuberculosis.

12425486

X-Linked Combined Immunodeficiency Diseases

Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency.

23028826

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