3.5.4.19: phosphoribosyl-AMP cyclohydrolase

This is an abbreviated version, for detailed information about phosphoribosyl-AMP cyclohydrolase, go to the full flat file.

Reaction

1-(5-phospho-beta-D-ribosyl)-AMP
+
H2O
=
1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide

Synonyms

HisI, N1-(5'-phosphoribosyl) adenosine-5'-monophosphate cyclohydrolase, phosphoribosyladenosine monophosphate cyclohydrolase, PR-AMP cyclohydrolase, PRA-CH, PRAMP-cyclohydrolase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.19 phosphoribosyl-AMP cyclohydrolase