3.5.4.17: adenosine-phosphate deaminase

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For detailed information about adenosine-phosphate deaminase, go to the full flat file.

Reaction

Synonyms

adenine nucleotide deaminase, adenosine (phosphate) deaminase, adenylate deaminase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.4 In cyclic amidines

                3.5.4.17 adenosine-phosphate deaminase

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Results	in table
1	Activating Compound
1	AA Sequence
1	CAS Registry Number
1	General Information
2	General Stability
28	Inhibitors
21	KM Value [mM]
4	Metals/Ions
4	Molecular Weight [Da]
9	Organism
3	Pathway
15	pH Optimum
2	pH Range
3	pH Stability
5	Purification (Commentary)
3	Reaction
1	Reaction Type
9	Reference
2	Source Tissue
5	Specific Activity [micromol/min/mg]
3	Storage Stability
53	Substrates and Products (Substrate)
2	Subunits
3	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
5	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 3.5.4.17 - adenosine-phosphate deaminase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

2'-AMP

Desulfovibrio desulfuricans

-

inhibits deamination of ATP

246706

3'-AMP

Desulfovibrio desulfuricans

-

inhibits deamination of ATP

246706

3'-IMP

Todarodes pacificus

-

competitive inhibition of deamination of adenosine 3'-phenylphosphonate

246709

adenine

Todarodes pacificus

-

competitive inhibition of deamination of adenosine 3'-phenylphosphonate

246709

adenosine

Desulfovibrio desulfuricans

-

inhibits deamination of ATP

246706

Ag+

Desulfovibrio desulfuricans

-

0.5 mM, complete inhibition of deamination of ATP

246706

beta,beta-dimethyl glutarate

Desulfovibrio desulfuricans

-

-

246706

cacodylate

Desulfovibrio desulfuricans

-

-

246706

citrate

Desulfovibrio desulfuricans

-

-

246706

Cl-

Desulfovibrio desulfuricans

-

-

246706

CN-

Desulfovibrio desulfuricans

-

non-competitive inhibition at low concentrations

246706

Co2+

Desulfovibrio desulfuricans

-

-

246706

CuSO4

Desulfovibrio desulfuricans

-

-

246706

F-

2 entries

Fe3+

Desulfovibrio desulfuricans

-

-

246706

Hg2+

Desulfovibrio desulfuricans

-

0.5 mM, complete inhibition of deamination of ATP

246706

Inosine

Todarodes pacificus

-

competitive inhibition of deamination of adenosine 3'-phenylphosphonate

246709

Maleate

Desulfovibrio desulfuricans

-

-

246706

Mn2+

2 entries

p-mercuribenzoate

Desulfovibrio desulfuricans

-

-

246706

PCMB

Porphyra crispata

-

-

246705

phosphate

Desulfovibrio desulfuricans

-

-

246706

purine riboside

Todarodes pacificus

-

competitive inhibition of deamination of adenosine 3'-phenylphosphonate

246709

succinate

Desulfovibrio desulfuricans

-

-

246706

Urea

Desulfovibrio desulfuricans

-

0.2-1 M

246706

Zn2+

Desulfovibrio desulfuricans

-

-

246706

F-

Desulfovibrio desulfuricans

-

non-competitive inhibition at low concentrations

246706

F-

Porphyra crispata

-

inhibits the deamination of ATP, NAD+, ADP and 5'-AMP to the extent of 90%, 90%, 86% and 80% respectively

246705

Mn2+

Desulfovibrio desulfuricans

-

-

246706

Mn2+

Porphyra crispata

-

inhibitor at neutral and alkaline pH. Activation at acidic pH

246705