3.5.4.11: pterin deaminase
This is an abbreviated version!
For detailed information about pterin deaminase, go to the full flat file.
Word Map on EC 3.5.4.11
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3.5.4.11
-
pterins
-
dictyostelium
-
discoideum
-
pteridines
-
folic
-
deamination
-
lumazines
-
amidohydrolase
-
mold
-
biopterin
-
slime
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isoxanthopterin
-
chemotaxis
-
guanine
-
amp
-
chemoattractant
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folate
-
amoebae
-
xanthopterin
-
sepiapterin
- 3.5.4.11
- pterins
- dictyostelium
- discoideum
- pteridines
-
folic
-
deamination
- lumazines
-
amidohydrolase
-
mold
- biopterin
-
slime
- isoxanthopterin
-
chemotaxis
- guanine
- amp
-
chemoattractant
- folate
-
amoebae
- xanthopterin
- sepiapterin
Reaction
Synonyms
acrasinase, Arad3529, PDA, Sgx9339a
ECTree
3.5.4.11 pterin deaminaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 3.5.4.11 - pterin deaminase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-amino-3,5-dihydropteridine-4,6-dione + H2O
1,5-dihydropteridine-2,4,6(3H)-trione + NH3
-
i.e. xanthopterin
-
-
?
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + H2O
2,4-dihydroxy-6-hydroxymethyl-7,8-dihydropteridine + NH3
2-amino-4-oxo-3,4-dihydropteridine-6-carboxylic acid + H2O
2,4-dioxo-1,2,3,4-tetrahydropteridine-6-carboxylic acid + NH3
2-amino-5,6,7,8-tetrahydropteridin-4(1H)-one + H2O
5,6,7,8-tetrahydropteridine-2,4(1H,3H)-dione + NH3
-
the enzyme specifically deaminates pterin, isoxanthopterin and tetrahydropterin
-
-
?
2-amino-6-hydroxypteridin-4(3H)-one + H2O
6-hydroxypteridine-2,4(1H,3H)-dione + NH3
-
i.e. 6-hydroxypterin
-
-
?
2-amino-6-methylpteridin-4(3H)-one + H2O
6-methylpteridine-2,4(1H,3H)-dione + NH3
-
i.e. 6-methylpterin
-
-
?
2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]pteridin-4(8H)-one + H2O
6-[(1R,2S)-1,2-dihydroxypropyl]pteridine-2,4(1H,3H)-dione + NH3
-
i.e. biopterin
-
-
?
2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydropteridin-4(1H)-one + H2O
6-[(2S)-2-hydroxypropanoyl]-7,8-dihydropteridine-2,4(1H,3H)-dione + NH3
-
i.e. sepiapterin
-
-
?
2-amino-7-methylpteridin-4(3H)-one + H2O
7-methylpteridine-2,4(1H,3H)-dione + NH3
-
i.e. 7-methylpterin
-
-
?
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + H2O
2,4-dihydroxy-6-hydroxymethyl-7,8-dihydropteridine + NH3
-
-
-
?
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + H2O
2,4-dihydroxy-6-hydroxymethyl-7,8-dihydropteridine + NH3
-
-
-
?
2-amino-4-hydroxypteridine + H2O
2,4-dihydroxypteridine + NH3
Alcaligenes metalcaligenes
-
i.e. pterin
i.e. lumazine
-
ir
2-amino-4-hydroxypteridine + H2O
2,4-dihydroxypteridine + NH3
-
i.e. pterin
i.e. lumazine
-
?
2-amino-4-hydroxypteridine + H2O
2,4-dihydroxypteridine + NH3
-
i.e. pterin. The enzyme specifically deaminates pterin, isoxanthopterin and tetrahydropterin
i.e. lumazine
-
?
2-amino-4-oxo-3,4-dihydropteridine-6-carboxylic acid + H2O
2,4-dioxo-1,2,3,4-tetrahydropteridine-6-carboxylic acid + NH3
-
i.e. pterin 6-carboxylate
i.e. 2,4-dioxo-pteridine-6-carboxylate
-
?
2-amino-4-oxo-3,4-dihydropteridine-6-carboxylic acid + H2O
2,4-dioxo-1,2,3,4-tetrahydropteridine-6-carboxylic acid + NH3
i.e. pterin 6-carboxylate
i.e. 2,4-dioxo-pteridine-6-carboxylate
-
?
2-aminopteridin-4(1H)-one + H2O
2-hydroxypteridin-4(1H)-one + NH3
-
-
-
?
2-aminopteridin-4(1H)-one + H2O
2-hydroxypteridin-4(1H)-one + NH3
-
-
-
?
2-aminopteridin-4(3H)-one + H2O
2-hydroxypteridin-4(3H)-one + NH3
-
-
-
?
2-aminopteridin-4(3H)-one + H2O
2-hydroxypteridin-4(3H)-one + NH3
-
-
-
?
2-aminopteridine-4,7(1H,8H)-dione + H2O
7-hydroxypteridine-2,4(1H,3H)-dione + NH3
-
i.e. isoxanthopterin. The enzyme specifically deaminates pterin, isoxanthopterin and tetrahydropterin
i.e. 7-hydroxylumazine
-
?
2-aminopteridine-4,7(1H,8H)-dione + H2O
7-hydroxypteridine-2,4(1H,3H)-dione + NH3
i.e. isoxanthopterin. The enzyme specifically deaminates pterin, isoxanthopterin and tetrahydropterin
i.e. 7-hydroxylumazine
-
?
additional information
?
-
Alcaligenes metalcaligenes
-
Only pteridines possessing the pterin structure (i.e. the 2-amino and 4-hydroxyl functional groups) are deaminated. The nature of the substitution at carbon 6 is relatively unimportant. However, an hydroxyl group at this position results in an inactive substance. Carbon 7 must be unsubstituted, since blocking of this position by a methyl or carboxyl function destroys the ability of the pterin to serve as a substrate. An N-5-formylated and reduced pterin is not deaminated
-
-
?
additional information
?
-
-
guanine, 7-carboxypterin, leucopterin, isoxanthopterin, and 6-methylisoxanthopterin do not serve as substrates
-
-
?
additional information
?
-
-
guanine, 7-carboxypterin, leucopterin, isoxanthopterin, and 6-methylisoxanthopterin do not serve as substrates
-
-
?
additional information
?
-
-
xanthopterin, biopterin, neopterin, pterin-6-carboxylic acid, and 6-hydroxymethylpterin are not deaminated
-
-
?
