3.5.4.10: IMP cyclohydrolase This is an abbreviated version! For detailed information about IMP cyclohydrolase, go to the full flat file .
Reaction
IMP +
H2O =
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
Synonyms 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, 5-aminoimidazole-4-carboxamide ribonucleotide tranformylase/IMP cyclohydrolase, AF1811, AICAR tranformylase/IMP cyclohydrolase, AICAR transformylase/IMP cyclohydrolase, AICAR transformylase/inosine 5'-monophosphate cyclohydrolase, AICAR-FT/IMP-CHase, AICAR-transformylase/IMP cyclohydrolase, ATIC, atic-1, IMP synthetase, IMPCH, IMPCHase, inosinate cyclohydrolase, inosine 5'-monophosphate cyclohydrolase, inosine monophosphate cyclohydrolase, inosinicase, ITGA2, MjPurO, MthPurO, PurH, PurH2, PurH2-type IMP cyclohydrolase, PurO, PurO-type IMP cyclohydrolase, TK0430
ECTree
Organism
Organism on EC 3.5.4.10 - IMP cyclohydrolase
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enzyme is expressed at nearly constant levels in both nondiapausing and prediapausing adults and downregulated by temperature in diapausing beetles stored at 10°C
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gene TM1249 or purH
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bifunctional protein, including EC 3.5.4.10 and EC 2.1.2.3
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bifunctional aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase
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bifunctional enzyme 5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase
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bifunctional enzyme 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase
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bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase
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bifunctional inosine monophosphate cyclohydrolase/AICAR transformylase. Female infant patient with lack in transformylase activity and about 40% residual enzymic activity, showing massive excretion of 5-amino-4-imidazolecarboxamide riboside, dysmorphic features, severe neurological defects, and congenital blindness
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gene ITGA2
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gene MJ0626
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gene MTH1020
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Harlan Sprague-Dawley
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