3.5.4.1: cytosine deaminase

This is an abbreviated version!
For detailed information about cytosine deaminase, go to the full flat file.

Word Map on EC 3.5.4.1

3.5.4.1

cytidine

deaminases

5-fluorocytosine

deamination

prodrugs

virion

hypermutation

viruses

5-fluorouracil

apolipoprotein

retroviruses

suicide

uracil

retroviral

apobecs

single-stranded

antiretroviral

polypeptide-like

mrna-editing

g-to-a

bystander

activation-induced

retrotransposons

anti-hiv-1

proviral

retroelements

lentiviruses

encapsidation

ganciclovir

deoxycytidine

retrotransposition

ssdna

fiv

samhd1

cullin

minus-strand

replication-competent

gene-directed

sivmac

medicine

line-1

hsv-tk

vpr

gdept

non-ltr

molecular biology

xenotropic

analysis

pharmacology

biotechnology

trim5alpha

diagnostics

proviruses

nickase

agriculture

single-cycle

elongins

Reaction

Synonyms

A3DE, APOBEC1, APOBEC3, APOBEC3G, CD, CDA, CDase, codA, CodA protein, Cytosine aminohydrolase, cytosine deaminase, cytosine deaminase I, cytosine deaminase II, cytosine deaminase P, cytosine deaminase S, cytosine deaminase Y, Fca1p, FCY1, isocytosine deaminase, yCD, Zn2+CDase

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.4 In cyclic amidines

3.5.4.1 cytosine deaminase

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Results	in table
112	Activating Compound
5545	AA Sequence
48	Application
1	CAS Registry Number
36	Cloned(Commentary)
11	Crystallization (Commentary)
3441	Disease/ Diagnostics
6	General Information
4	General Stability
35	IC50 Value
196	Inhibitors
18	kcat/KM [mM/s]
4	Ki Value [mM]
84	KM Value [mM]
11	Localization
31	Metals/Ions
46	Molecular Weight [Da]
209	Natural Substrates/ Products (Substrates)
296	Organism
4	Oxidation Stability
6	Pathway
42	PDB ID
19	pH Optimum
1	pH Range
6	pH Stability
76	Protein Variants
36	Purification (Commentary)
4	Reaction
233	Reference
2	Source Tissue
64	Specific Activity [micromol/min/mg]
6	Storage Stability
365	Substrates and Products (Substrate)
28	Subunits
41	Synonyms
1	Systematic Name
20	Temperature Optimum [°C]
1	Temperature Range [°C]
11	Temperature Stability [°C]
57	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.5.4.1 - cytosine deaminase

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0.0013

(1R,2S)-(-)-ephedrine

Homo sapiens

pH 7.4, 37°C

718465

0.00036

(alpha-D-glucopyranosylthio)gold

Homo sapiens

pH 7.4, 37°C

718465

0.013

(R)-2,10,11-trihydroxy-N-propyl-noraporphine

Homo sapiens

pH 7.4, 37°C

718465

0.0017

(R)-2,10,11-trihydroxyaporphine

Homo sapiens

pH 7.4, 37°C

718465

0.0013

(R)-apomorphine

Homo sapiens

pH 7.4, 37°C

718465

0.0029

(R)-N-allylnorapomorphine

Homo sapiens

pH 7.4, 37°C

718465

0.006

(R)-propylnorapomorphine

Homo sapiens

pH 7.4, 37°C

718465

0.0053

(S)-carbidopa

Homo sapiens

pH 7.4, 37°C

718465

0.027

1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol

Homo sapiens

pH 7.4, 37°C

718465

0.019

3,4-dihydroxyphenylacetic acid

Homo sapiens

pH 7.4, 37°C

718465

0.00013

4-chloromercuribenzoic acid

Homo sapiens

pH 7.4, 37°C

718465

0.0035

4-[(2-sulfanyl-1H-imidazol-1-yl)methyl]phenol

Homo sapiens

pH 7.4, 37°C

718465

0.0064

5'-guanidinonaltrindole

Homo sapiens

pH 7.4, 37°C

718465

0.0007

6-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene

Homo sapiens

pH 7.4, 37°C

718465

0.004

6-hydroxy-DL-DOPA

Homo sapiens

pH 7.4, 37°C

718465

0.00049

aurintricarboxylic acid

Homo sapiens

pH 7.4, 37°C

718465

0.085

caffeic acid

Homo sapiens

pH 7.4, 37°C

718465

0.0075

cephapirin

Homo sapiens

pH 7.4, 37°C

718465

0.00043 - 0.0091

dephostatin

2 entries

0.00059

dihydrexidine

Homo sapiens

pH 7.4, 37°C

718465

0.0028

ebselen

Homo sapiens

pH 7.4, 37°C

718465

0.6

ganciclovir

Escherichia coli

P25524

37°C, recombinant fusion protein HSV-1TKglyCD

684863

0.002

hispidin

Homo sapiens

pH 7.4, 37°C

718465

0.0026

hydroquinone

Homo sapiens

pH 7.4, 37°C

718465

0.003

iodoacetamide

Homo sapiens

pH 7.4, 37°C

718465

0.013

methyl 3-hydroxy-DL-tyrosinate

Homo sapiens

pH 7.4, 37°C

718465

0.0034

myricetin

Homo sapiens

pH 7.4, 37°C

718465

0.00045

N-acetyldopamine

Homo sapiens

pH 7.4, 37°C

718465

0.0088

nordihydroguaiaretic acid

Homo sapiens

pH 7.4, 37°C

718465

0.00017

p-benzoquinone

Homo sapiens

pH 7.4, 37°C

718465

0.0018

piceatannol

Homo sapiens

pH 7.4, 37°C

718465

0.0056

PPNDS tetrasodium

Homo sapiens

pH 7.4, 37°C

718465

0.029

SCH202676

Homo sapiens

pH 7.4, 37°C

718465

0.0013

SKF-89626

Homo sapiens

pH 7.4, 37°C

718465