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3.5.4.1: cytosine deaminase

This is an abbreviated version!
For detailed information about cytosine deaminase, go to the full flat file.

Word Map on EC 3.5.4.1

Reaction

cytosine
+
H2O
=
Uracil
+
NH3

Synonyms

A3DE, APOBEC1, APOBEC3, APOBEC3G, CD, CDA, CDase, codA, CodA protein, Cytosine aminohydrolase, cytosine deaminase, cytosine deaminase I, cytosine deaminase II, cytosine deaminase P, cytosine deaminase S, cytosine deaminase Y, Fca1p, FCY1, isocytosine deaminase, yCD, Zn2+CDase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.1 cytosine deaminase

General Stability

General Stability on EC 3.5.4.1 - cytosine deaminase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
conjugation of poly-L-lysine to cytosine deaminase increases the enzyme's stability after uptake into cells, mechanism, overview
-
exceptionally stable to denaturation
-
stable in cell-free extracts
-
unstable in absence of reducing agents
-