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3.5.3.7: guanidinobutyrase

This is an abbreviated version!
For detailed information about guanidinobutyrase, go to the full flat file.

Word Map on EC 3.5.3.7

Reaction

4-Guanidinobutanoate
+
H2O
=
4-aminobutanoate
+
Urea

Synonyms

4-guanidinobutyrase, 4-guanidinobutyrate amidinobutyrase, G-Base, gamma-guanidinobutyrate amidinohydrolase, gamma-guanidobutyrase, GBase, GBH, GBU1, GbuA, guanidinobutyrase, guanidinobutyrate ureahydrolase, More, tench liver isoenzyme II, Zn2+-guanidinobutyrase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.3 In linear amidines
                3.5.3.7 guanidinobutyrase

Inhibitors

Inhibitors on EC 3.5.3.7 - guanidinobutyrase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
2-mercaptoethanol
-
-
2-mercaptopropionate
-
-
2-nitrobenzoic acid
-
slight inhibition
3-mercaptoethylamine
-
-
3-Mercaptopropionate
-
-
4-aminobutyrate
-
-
5-Aminovalerate
6-aminocaproate
-
-
Mercaptoacetate
strong mixed-type inhibitor
mercaptoethylamine
-
-
Mn2+
-
5 mM complete inhibition
n-Butyrate
N-ethylmaleimide
-
slight inhibition
o-phenanthroline
-
-
p-chloromercuribenzoate
-
reactivation by incubation with 2-mercaptoethanol
propionate
-
competitive inhibition
trans-crotonate
-
-
Zn2+
-
92% inhibition
additional information
-