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3.5.3.6: arginine deiminase

This is an abbreviated version!
For detailed information about arginine deiminase, go to the full flat file.

Word Map on EC 3.5.3.6

Reaction

L-arginine
+
H2O
=
L-citrulline
+
NH3

Synonyms

ADI, ArcA, arcA-1, arcA-2, arginine deiminase, arginine dihydrolase, arginine-degrading enzyme, citrulline iminase, deiminase, arginine, L-arginine deiminase, LADI, lymphocyte blastogenesis inhibitory factor, More, PaADI, PAD, PAD2, peptidylarginine deiminase, PpADI, Streptococcal acid glycoprotein

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.3 In linear amidines
                3.5.3.6 arginine deiminase

KCat KM Value

KCat KM Value on EC 3.5.3.6 - arginine deiminase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00023
agmatine-L-Arg
-
-
0.00099
benzoyl-L-arginine ethyl ester
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.21
bradykinin antagonist-L-Arg
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
2.1
bradykinin-L-Arg
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.031
D-Arg
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.024
homoarginine
-
-
0.000215 - 0.000277
L-alanine
0.19
L-Arg
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.00018 - 189.06
L-arginine
0.022
L-Arginine hydroxamate
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.00093
L-canavanine-L-Arg
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.000215 - 0.00032
L-lysine
0.11
L-Pro-L-Arg-L-Phe
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
1.9
L-Pro-L-Phe-L-Arg
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
6 - 12
N-alpha-benzoyl-L-arginine
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.005 - 18
N-alpha-benzoyl-L-arginine ethyl ester
2.3
Nalpha-benzoyl-L-arginine
in 50 mM K+-HEPES (pH 7.5), at 25°C
0.29
Nomega-amino-L-arginine
in 50 mM K+-HEPES (pH 7.5), at 25°C
0.003
Nomega-hydroxy-L-arginine
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C