3.5.3.2: guanidinoacetase

This is an abbreviated version!
For detailed information about guanidinoacetase, go to the full flat file.

Reaction

Synonyms

glycocyaminase

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.3 In linear amidines

3.5.3.2 guanidinoacetase

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Results	in table
7	Activating Compound
3	Application
1	CAS Registry Number
2	Crystallization (Commentary)
27	Inhibitors
1	Ki Value [mM]
3	KM Value [mM]
14	Metals/Ions
10	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
56	Organism
4	pH Optimum
1	pH Range
2	pH Stability
5	Purification (Commentary)
1	Reaction
1	Reaction Type
26	Reference
4	Specific Activity [micromol/min/mg]
2	Storage Stability
44	Substrates and Products (Substrate)
8	Subunits
1	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 3.5.3.2 - guanidinoacetase

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1,10-phenanthroline

8-hydroxyquinoline

ATP

1.0 mM 50% inhibition

209435

Co2+

Pseudomonas sp.

1 mM, plus 0.1 mM Mn2+ complete inhibition

209435

Cu2+

Pseudomonas sp.

1 mM plus 0.1 mM Mn2+ complete inhibition

209435

DTNB

Flavobacterium sp.

inhibits the reaction slightly

209437

EDTA

Pseudomonas sp.

complete loss of activity, fully restored with Mn2+

209435

Fe2+

2 entries

glycine

Corynebacterium sp.

competitive inhibition

Hg2+

Iodine

n-butylguanidine

n-Decylamine

n-dodecylamine

n-octylamine

n-propylguanidine

Ni2+

1 mM, plus 0.1 mM Mn2+ complete inhibition

209435

p-chloromercuribenzoate

3 entries

Zn2+

Pseudomonas sp.

1 mM, plus 0.1 mM Mn2+ complete inhibition

209435