3.5.3.18: dimethylargininase

This is an abbreviated version!
For detailed information about dimethylargininase, go to the full flat file.

Word Map on EC 3.5.3.18

3.5.3.18

endothelial

cardiovascular

artery

hypertension

angiotensin

l-citrulline

aortic

umbilical

vasodilation

vein

endothelium-dependent

dimethylamine

atherosclerosis

coronary

methylarginines

ng,ng-dimethylarginine

homocysteine

medicine

huvecs

endothelium-derived

hyperhomocysteinemia

nnos

l-nmma

ii-induced

ng-monomethyl-l-arginine

monomethylarginine

ox-ldl

analysis

Reaction

Synonyms

Adv-DDAH, DDAH, DDAH-1, DDAH-2, DDAH-I, DDAH1, DDAH2, DDAHI, DDAHII, dimethlarginine dimethylaminohydrolase, dimethylaminohydrolase, Dimethylargininase, dimethylarginine dimethylamino-hydrolase, dimethylarginine dimethylaminohydrolase, dimethylarginine dimethylaminohydrolase 1, dimethylarginine dimethylaminohydrolase isoform 1, dimethylarginine dimethylaminohydrolase-2, dimethylarginine dimethylaminohydrolase1, dimethylarginine-dimethylaminohydrolase, G6a, hDDAH-1, human DDAH-1, human dimethylarginine dimethylaminohydrolase-1, Nomega,Nomega-dimethyl-L-arginine dimethylaminohydrolase-1, PA1195, PaDDAH

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.3 In linear amidines

3.5.3.18 dimethylargininase

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Results	in table
47	Activating Compound
2707	AA Sequence
30	Application
1	CAS Registry Number
19	Cloned(Commentary)
3	Crystallization (Commentary)
778	Disease/ Diagnostics
8	Expression
12	General Information
1	General Stability
20	IC50 Value
138	Inhibitors
8	kcat/KM [mM/s]
26	Ki Value [mM]
34	KM Value [mM]
6	Localization
3	Metals/Ions
18	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
92	Organism
37	PDB ID
11	pH Optimum
2	pH Range
2	pH Stability
29	Protein Variants
12	Purification (Commentary)
1	Reaction
6	Reaction Type
88	Reference
3	Renatured (Commentary)
165	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
92	Substrates and Products (Substrate)
7	Subunits
138	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
3	Temperature Stability [°C]
20	Turnover Number [1/s]

KM Value

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KM Value on EC 3.5.3.18 - dimethylargininase

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0.18

dimethyl-L-arginine

5 entries

0.133

N,N-dimethyl-L-arginine

Homo sapiens

pH 7.4, 37°C

720116

0.13

N5-(methoxycarbamimidoyl)-L-ornithine

Homo sapiens

37°C, 30 min, pH 7.4

696709

0.106

N5-(methylcarbamimidoyl)-L-ornithine

Homo sapiens

37°C, 30 min, pH 7.4

696709

0.161

N5-[2,5-dihydro-1H-pyrrol-1-yl(imino)methyl]-L-ornithine

Homo sapiens

37°C, 30 min, pH 7.4

696709

0.039 - 9.24

NG,NG-dimethyl-L-arginine

6 entries

NG,NG-Dimethyl-L-homoarginine

Rattus norvegicus

288971

1.11

NG-Amino-L-arginine

Pseudomonas aeruginosa

Q9I4E3

667675

2.3

NG-Hydroxy-L-arginine

Pseudomonas aeruginosa

Q9I4E3

667675

0.044 - 0.67

NG-methyl-L-arginine

3 entries

0.36 - 1.6

NG-monomethyl-L-arginine

3 entries

0.11 - 13.7

Nomega,Nomega-dimethyl-L-arginine

4 entries

0.0014 - 0.143

S-methyl-L-thiocitrulline

6 entries