3.5.3.16: methylguanidinase

This is an abbreviated version!
For detailed information about methylguanidinase, go to the full flat file.

Reaction

Synonyms

methylguanidine hydrolase, methylguanidine-decomposing enzyme

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.3 In linear amidines

                3.5.3.16 methylguanidinase

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Results	in table
2	Application
1	CAS Registry Number
2	Natural Substrates/ Products (Substrates)
2	Organism
1	Pathway
1	Purification (Commentary)
1	Reaction
1	Reaction Type
2	Reference
1	Specific Activity [micromol/min/mg]
12	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 3.5.3.16 - methylguanidinase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

agmatine + H2O

?

Alcaligenes sp.

-

slight hydrolysis, 1.3% of the natural substrate methylguanidine

209433

-

-

?

ethylguanidine + H2O

ethylamine + urea

2 entries

guanidine + H2O

NH3 + urea

Alcaligenes sp.

-

slight hydrolysis, 1.3% of the natural substrate methylguanidine

209433

-

-

?

methylguanidine + H2O

methylamine + urea

2 entries

n-butylguanidine + H2O

n-butylamine + urea

2 entries

n-propylguanidine + H2O

n-propylamine + urea

2 entries

additional information

?

-

2 entries

ethylguanidine + H2O

ethylamine + urea

Alcaligenes sp.

-

slight hydrolysis, 1.3% of the natural substrate methylguanidine

209433

-

-

?

ethylguanidine + H2O

ethylamine + urea

Alcaligenes sp. N-42

-

slight hydrolysis, 1.3% of the natural substrate methylguanidine

209433

-

-

?

methylguanidine + H2O

methylamine + urea

Alcaligenes sp.

-

-

209433

-

-

?

methylguanidine + H2O

methylamine + urea

Alcaligenes sp. N-42

-

-

209433

-

-

?

n-butylguanidine + H2O

n-butylamine + urea

Alcaligenes sp.

-

slight hydrolysis, 1.3% of the natural substrate methylguanidine

209433

-

-

?

n-butylguanidine + H2O

n-butylamine + urea

Alcaligenes sp. N-42

-

slight hydrolysis, 1.3% of the natural substrate methylguanidine

209433

-

-

?

n-propylguanidine + H2O

n-propylamine + urea

Alcaligenes sp.

-

slight hydrolysis, 1.3% of the natural substrate methylguanidine

209433

-

-

?

n-propylguanidine + H2O

n-propylamine + urea

Alcaligenes sp. N-42

-

slight hydrolysis, 1.3% of the natural substrate methylguanidine

209433

-

-

?

additional information

?

-

Alcaligenes sp.

-

no hydrolysis of guanidino compounds with carboxyl group

209433

-

-

?

additional information

?

-

Alcaligenes sp. N-42

-

no hydrolysis of guanidino compounds with carboxyl group

209433

-

-

?