3.5.3.11: agmatinase

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For detailed information about agmatinase, go to the full flat file.

Word Map on EC 3.5.3.11

3.5.3.11

putrescine

polyamine

ornithine

imidazoline

speb

arcaine

proclavaminate

idazoxan

slc7a1

efaroxan

Reaction

Synonyms

AGM-1, AGMAT, agmatinase, agmatinase-like protein, agmatine ureohydrolase, Alr2310, APL, AUH, HVO_2299, MJ0309, N130D variant of arginase type I, Proclavaminic acid amidino hydrolase, SpeB

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.3 In linear amidines

3.5.3.11 agmatinase

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Results	in table
4	Activating Compound
12374	AA Sequence
1	CAS Registry Number
8	Cloned(Commentary)
3	Crystallization (Commentary)
37	Disease/ Diagnostics
2	Expression
8	General Information
1	General Stability
24	Inhibitors
5	kcat/KM [mM/s]
4	Ki Value [mM]
18	KM Value [mM]
1	Localization
13	Metals/Ions
12	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
3	Organic Solvent Stability
39	Organism
6	Pathway
83	PDB ID
5	pH Optimum
2	pH Range
18	Protein Variants
7	Purification (Commentary)
1	Reaction
1	Reaction Type
39	Reference
28	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
23	Substrates and Products (Substrate)
8	Subunits
27	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
4	Temperature Stability [°C]
12	Turnover Number [1/s]

Source Tissue

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Source Tissue on EC 3.5.3.11 - agmatinase

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agmatinase is localised pre- and postsynaptically, to dendritic spines, spine and non-spine terminals, and dendritic profiles. In dendritic spines, labelling displayed a tendency towards the postsynaptic density

the enzyme is localized in the apical and subapical region of mature hyphae, localizing at the Spitzenkörper and at the endocytic collar closely resembling the F-actin population

753719

hypothalamus

Rattus norvegicus

in glial cells and arcuate nucleus neurons of the hypothalamus

712119

kidney

Homo sapiens

agmatinase in normal kidneys is restricted to tubulus epithelial cells, while in tumors activity is low and heterogeneous

665228

kidney tumor cell

Homo sapiens

agmatinase in normal kidneys is restricted to tubulus epithelial cells, while in tumors activity is low and heterogeneous

additional information

Rattus norvegicus

the protein is not detected in brain cortex

712119