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3.5.2.5: allantoinase

This is an abbreviated version!
For detailed information about allantoinase, go to the full flat file.

Word Map on EC 3.5.2.5

Reaction

(S)-allantoin
+
H2O
=
Allantoate

Synonyms

AaALN, allantoin amidohydrolase, allantoinase, ALLase, AllBali, ALN, aln-1, aln-2, Fe-allantoinase, IsoI, IsoII, metal-dependent allantoinase, metal-independent allantoinase, Os04g0680400, OsALN, puuE, Salk_142607, Salk_146783, zinc-amended allantoinase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.2 In cyclic amides
                3.5.2.5 allantoinase

Expression

Expression on EC 3.5.2.5 - allantoinase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
allantoin accumulation is mediated by allantoinase downregulation. The AtALN promoter activity is present in specific plant tissues during plant development and is strongly repressed by salt stress
at the onset of flowering, allantoinase gene expression and enzyme increase in shoots and leaves from plants using symbiotically fixed nitrogen as the sole nitrogen source activity
-
the genes involved in the conversion of allantoin into allantoate and in the deamination of guanine to xanthine are organized in three transcriptional units, hpxSAB, hpxC, and guaD. hpxSAB, which includes hpxB encoding allantoinase, is the most tightly regulated unit. This operon is activated by growth on allantoin as a nitrogen source. Addition of allantoin to nitrogen excess cultures does not result in hpxSAB induction. Full induction of hpxSAB by allantoin requires both HpxS, encoding a regulatory protein of the GntR family, and nitrogen assimilation control protein NAC
-
the OsALN gene expression is decreased during prolongated N application, overview
the OsALN gene expression is increased during N starvation, overview