3.5.2.12: 6-aminohexanoate-cyclic-dimer hydrolase

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For detailed information about 6-aminohexanoate-cyclic-dimer hydrolase, go to the full flat file.

Word Map on EC 3.5.2.12

3.5.2.12

6-aminohexanoate-dimer

arthrobacter

flavobacterium

acidovorax

compendium

amides

hydrolases

hydrolysing

sphingomonas

man-made

cupriavidus

Reaction

Synonyms

6-aminohexanoate-cyclic- dimer hydrolase (Caulobacter crescentus gene CC1323), 6-aminohexanoate-cyclic- dimer hydrolase (Deinococcus radiodurans strain R1 gene DR0235), 6-aminohexanoate-cyclic-dimer hydrolase, Acd hydrolase, hydrolase, aminocaproate cyclic dimer, Nylon oligomers degrading enzyme EI, omega-laurolactam hydrolase

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.2 In cyclic amides

3.5.2.12 6-aminohexanoate-cyclic-dimer hydrolase

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Results	in table
718	AA Sequence
3	CAS Registry Number
10	Cloned(Commentary)
7	Crystallization (Commentary)
5	Inhibitors
6	kcat/KM [mM/s]
8	KM Value [mM]
5	Localization
5	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
55	Organism
3	Pathway
2	PDB ID
8	pH Optimum
2	pH Range
1	pH Stability
11	Protein Variants
5	Purification (Commentary)
2	Reaction
11	Reaction Type
30	Reference
18	Specific Activity [micromol/min/mg]
45	Substrates and Products (Substrate)
3	Subunits
16	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
5	Temperature Stability [°C]
8	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 3.5.2.12 - 6-aminohexanoate-cyclic-dimer hydrolase

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1,8-diazacyclotetradecane-2,9-dione + H2O

N-(6-aminohexanoyl)-6-aminohexanoate

18 entries

6-amino-hexanoate cyclic dimer + H2O

6-aminohexanoate linear dimer

Paenarthrobacter ureafaciens

712418

6-amino-hexanoate-cyclic-dimer + H2O

Rhodococcus sp. U-224

B5MF68

assay at pH 7.0, 30°C, 48 h

696817

omega-laurolactam + H2O

12-aminolauric acid

11 entries

omega-octalactam + H2O

2 entries

additional information

Paenarthrobacter ureafaciens

enzyme additionally catalyzes the hydrolysis of amide compounds and esters such as glutamine, malonamide, indoleacetamide, 4-nitrophenylacetate, with a specific activity beolw 0.5% of the activity with 6-amino-hexanoate cyclic dimer

712418