3.5.2.12: 6-aminohexanoate-cyclic-dimer hydrolase

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For detailed information about 6-aminohexanoate-cyclic-dimer hydrolase, go to the full flat file.

Reaction

Synonyms

6-aminohexanoate-cyclic- dimer hydrolase (Caulobacter crescentus gene CC1323), 6-aminohexanoate-cyclic- dimer hydrolase (Deinococcus radiodurans strain R1 gene DR0235), 6-aminohexanoate-cyclic-dimer hydrolase, Acd hydrolase, hydrolase, aminocaproate cyclic dimer, Nylon oligomers degrading enzyme EI, omega-laurolactam hydrolase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.2 In cyclic amides

                3.5.2.12 6-aminohexanoate-cyclic-dimer hydrolase

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Results	in table
718	AA Sequence
3	CAS Registry Number
10	Cloned(Commentary)
7	Crystallization (Commentary)
5	Inhibitors
6	kcat/KM [mM/s]
8	KM Value [mM]
5	Localization
5	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
55	Organism
3	Pathway
2	PDB ID
8	pH Optimum
2	pH Range
1	pH Stability
11	Protein Variants
5	Purification (Commentary)
2	Reaction
11	Reaction Type
30	Reference
18	Specific Activity [micromol/min/mg]
45	Substrates and Products (Substrate)
3	Subunits
16	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
5	Temperature Stability [°C]
8	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.5.2.12 - 6-aminohexanoate-cyclic-dimer hydrolase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.004

Pseudomonas sp.

-

-

172039

0.02

Flavobacterium sp.

-

-

172042

0.04

Paenarthrobacter ureafaciens

-

mutant C316E, pH 7.0, 30°C

712418

0.063

Paenarthrobacter ureafaciens

-

mutant C316D, pH 7.0, 30°C

712418

0.15

Paenarthrobacter ureafaciens

-

mutant C316K, pH 7.0, 30°C

712418

0.18

Paenarthrobacter ureafaciens

-

mutant C316N, pH 7.0, 30°C

712418

0.29

Sphingomonas sp. U238

B7XC00

assay at 30°C, total incubation time 20 h

696855

0.36

Rhodococcus sp. U-224

-

assay at 30°C, total incubation time 20 h

696855

0.57

Paenarthrobacter ureafaciens

-

mutant N125A, pH 7.0, 30°C

712418

0.73

Paenarthrobacter ureafaciens

-

mutant C316A, pH 7.0, 30°C

712418

1.22

Cupriavidus sp. T7

B7XBZ7

-

696855

1.29

Cupriavidus sp. U124

B7XBZ9

assay at 30°C, total incubation time 20 h

696855

2.77

Acidovorax sp. T31

B7XBZ8

assay at 30°C, total incubation time 20 h

696855

4.1

Paenarthrobacter ureafaciens

-

wild-type, pH 7.0, 30°C

712418

4.46

Paenarthrobacter ureafaciens

-

mutant C316S, pH 7.0, 30°C

712418

6.54

Rhodococcus sp. U-224

B5MF68

-

696817

7.7

Paenarthrobacter ureafaciens

-

mutant C316G, pH 7.0, 30°C

712418

8.26

Acidovorax sp. T31

B7XBZ8

assay at 37°C, incubation for 12 h

696855