3.5.1.B18: 4-aminobenzoylglutamate hydrolase

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For detailed information about 4-aminobenzoylglutamate hydrolase, go to the full flat file.

Reaction

Synonyms

p-aminobenzoylglutamate hydrolase, pABAGlu hydrolase, PGH

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.B18 4-aminobenzoylglutamate hydrolase

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Results	in table
1	CAS Registry Number
1	IC50 Value
12	Inhibitors
2	KM Value [mM]
3	Localization
6	Metals/Ions
1	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
5	Organism
5	pH Optimum
1	pH Range
1	Purification (Commentary)
2	Reaction
5	Reference
12	Source Tissue
6	Specific Activity [micromol/min/mg]
20	Substrates and Products (Substrate)
1	Subunits
15	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]

Inhibitors

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Inhibitors on EC 3.5.1.B18 - 4-aminobenzoylglutamate hydrolase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1,10-phenanthroline

Arabidopsis thaliana

-

25% inhibition at 0.1 mM

683975

8-Hydroxyquinoline-5-sulfonate

Arabidopsis thaliana

-

complete inhibition at 1 mM

683975

Cu2+

Arabidopsis thaliana

-

complete inhibition

683975

DTNB

Arabidopsis thaliana

-

25% inhibition at 1 mM

683975

DTT

Arabidopsis thaliana

-

53% inhibition at 1 mM

683975

EDTA

Arabidopsis thaliana

-

21% inhibition at 1 mM

683975

folate

Arabidopsis thaliana

-

substrate inhibition, competitive

683975

Hg2+

Arabidopsis thaliana

-

complete inhibition

683975

N,N,N',N'-tetrakis[2-pyridylmethyl]ethylenediamine

Arabidopsis thaliana

-

i.e. TPEN, 53% inhibition at 0.1 mM

683975

pepstatin

Arabidopsis thaliana

-

25% inhibition at 0.0015 mM

683975

PMSF

Arabidopsis thaliana

-

15% inhibition at 1 mM

683975

additional information

Arabidopsis thaliana

-

the enzyme activity is fairly insensitive to serine, cysteine, and aspartic reagents, but is inhibited by metal chelators

683975

-