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3.5.1.93: glutaryl-7-aminocephalosporanic-acid acylase

This is an abbreviated version!
For detailed information about glutaryl-7-aminocephalosporanic-acid acylase, go to the full flat file.

Word Map on EC 3.5.1.93

Reaction

(7R)-7-(4-carboxybutanamido)cephalosporanate
+
H2O
=
(7R)-7-aminocephalosporanate
+
Glutarate

Synonyms

7beta-(4-carboxybutanamido)cephalosporanic acid acylase, AcyI, acylase ACY 1 proenzyme, adipyl-cephalosporin acylase, antibiotic acylase, CA, CCA, cephalorin acylase, cephalosporin acylase, cephalosporin acylase II, cephalosporin C acylase, cephalosporin-C acylase, CephC acylase, class III acylase, class III GA, class III glutaryl acylase, CPC acylase, CPCAcy, GA, GAR, GCA, GL-7-ACA acylase, GL-7ACA acylase, Gl7ACA acylase, GLA, glutaryl 7-amino cephalosporanic acid acylase, glutaryl 7-aminocephalosporanic acid acylase, glutaryl acylase, glutaryl-7-(7-aminocephalosporanic acid) acylase, glutaryl-7-ACA acylase, glutaryl-7-amino cephalosporanic acid acylase, glutaryl-7-aminocephalosporanic acid acylase, glutaryl-7-aminocephalosporic acid acylase, J1 acylase, N176 cephalosporin C acylase, sCPCAcy, VAC, VAC acylase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase

Turnover Number

Turnover Number on EC 3.5.1.93 - glutaryl-7-aminocephalosporanic-acid acylase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.16
4-(glutarylamino)benzoic acid
-
at 37°C, pH not specified in the publication
0.0485 - 0.508
7-aminocephalosporanic acid
0.015 - 1.16
adipyl-7-aminocephalosporanic acid
0.002 - 1.9
adipyl-7-aminodeacetoxycephalosporanic acid
0.34 - 1.9
adipyl-7-aminodesacetoxycephalosporanic acid
0.015 - 10.4
cephalosporin C
0.33
gamma-Glu-Cys-Gly
-
at 37°C, pH not specified in the publication
0.008 - 49.8
glutaryl-7-aminocephalosporanic acid
6.2
glutaryl-alanyl-proline
-
at 37°C, pH not specified in the publication
12.8
glutaryl-EGDPPDLADQG
-
at 37°C, pH not specified in the publication
3.2
glutaryl-gamma-Glu-Cys-Gly
-
at 37°C, pH not specified in the publication
4.8
glutaryl-GDAADAADKG
-
at 37°C, pH not specified in the publication
13.8
glutaryl-GDPP
-
at 37°C, pH not specified in the publication
13.2
glutaryl-GDPPDLADQG
-
at 37°C, pH not specified in the publication
1.36
glutaryl-GGGGAA
-
at 37°C, pH not specified in the publication
1.73
glutaryl-GGGGGK
-
at 37°C, pH not specified in the publication
1.65
glutaryl-glycine
-
at 37°C, pH not specified in the publication
5.4
glutaryl-glycyl-proline
-
at 37°C, pH not specified in the publication
3.1
glutaryl-tryptophan
-
at 37°C, pH not specified in the publication
0.35
glutarylaniline
-
at 37°C, pH not specified in the publication
1.28
succinyl-7-aminocephalosporanic acid
-
at 37°C, pH not specified in the publication
additional information
glutaryl-7-aminocephalosporanic acid
-
pH 8.0, 37°C, mutant enzyme Y126F