3.5.1.9: arylformamidase
This is an abbreviated version!
For detailed information about arylformamidase, go to the full flat file.
Word Map on EC 3.5.1.9
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3.5.1.9
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organophosphorus
-
l-tryptophan
-
formylation
-
teratogen
-
n-formyl-l-kynurenine
-
teratogenesis
-
methylcarbamate
-
l-kynurenine
-
diazinon
-
parvulus
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pyrimidinyls
-
kynurenic
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xanthurenic
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triesters
-
degradation
-
formyltransferase
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crotonamide
- 3.5.1.9
-
organophosphorus
- l-tryptophan
-
formylation
-
teratogen
- n-formyl-l-kynurenine
-
teratogenesis
- methylcarbamate
- l-kynurenine
- diazinon
- parvulus
-
pyrimidinyls
-
kynurenic
-
xanthurenic
-
triesters
- degradation
-
formyltransferase
- crotonamide
Reaction
Synonyms
AFMID, Bna7p, FKF, formamidase I, formamidase II, formyl kynurenine formamidase, formylase, formylkynureninase, formylkynurenine formamidase, KFA, KFase, KynB, kynurenine formamidase, kynurine formamidase
ECTree
3.5.1.9 arylformamidaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 3.5.1.9 - arylformamidase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
5-hydroxyformyl-DL-kynurenine + H2O
5-hydroxy-DL-kynurenine + formate
-
-
-
?
N-formyl-m-aminobenzoic acid + H2O
formate + m-aminobenzoic acid
-
very low activity
-
?
N-formyl-o-aminonitrobenzene + H2O
formate + o-nitroaniline
-
low activity
-
?
additional information
?
-
-
an enzyme other than the aryl formamidase additionally catalyzes the formation of L-kynurenine in kidney
-
-
?
N-formyl-L-kynurenine + H2O
formate + L-kynurenine
the enzyme forms part of the kynurenine pathway which metabolises tryptophan to anthranilate
-
-
?
N-formyl-L-kynurenine + H2O
formate + L-kynurenine
the enzyme forms part of the kynurenine pathway which metabolises tryptophan to anthranilate
-
-
?
N-formyl-L-kynurenine + H2O
formate + L-kynurenine
Gallus gallus White leghorns
-
-
-
?
N-formyl-L-kynurenine + H2O
formate + L-kynurenine
-
step in tryptophan metabolism and biosynthesis of kynurenine-derived derivatives, e.g. kynurenic acid, quinolinic acid, nicotinamide, NAD+, and NADP+, pathway disruption causes neurotoxicity and immunotoxicity, overview
-
-
?
N-formyl-L-kynurenine + H2O
formate + L-kynurenine
-
-
-
?
N-formyl-L-kynurenine + H2O
L-kynurenine + formate
-
involved in the pathway of tryptophan degradation
-
?
N-formyl-L-kynurenine + H2O
L-kynurenine + formate
-
formation of alcohol esters in the presence of alcohols
-
?
N-formyl-L-kynurenine + H2O
L-kynurenine + formate
-
unable to transfer a formyl group directly to tetrahydrofolic acid
-
?
N-formyl-L-kynurenine + H2O
L-kynurenine + formate
-
involved in the pathway of tryptophan degradation
-
?
N-formyl-L-kynurenine + H2O
L-kynurenine + formate
-
preferred substrate, involved in formation of antibiotics and NAD+
-
?
N-formyl-L-kynurenine + H2O
L-kynurenine + formate
-
formamidase II is an integral component of the actinomycin-synthesizing system
-
?
N-formyl-o-aminoacetophenone + H2O
formate + o-aminoacetophenone
-
-
-
?
N-formyl-o-aminoacetophenone + H2O
formate + o-aminoacetophenone
-
low activity
-
?
N-formyl-o-aminoacetophenone + H2O
formate + o-aminoacetophenone
-
22% of activity compared to N-formyl-L-kynurenine
-
?
N-formyl-o-aminoacetophenone + H2O
formate + o-aminoacetophenone
-
-
-
?
N-formyl-o-aminoacetophenone + H2O
formate + o-aminoacetophenone
-
60% of activity compared to N-formyl-L-kynurenine
-
?
N-formyl-o-aminoacetophenone + H2O
formate + o-aminoacetophenone
-
low activity for both formamidases I and II
-
?
N-formyl-o-aminoacetophenone + H2O
formate + o-aminoacetophenone
-
low activity for both formamidases I and II
-
?
N-formyl-o-aminoacetophenone + H2O
formate + o-aminoacetophenone
-
the only substrate
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
formation of alcohol esters in the presence of alcohols
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
24% of activity compared to N-formyl-L-kynurenine
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
10times slower hydrolysis than for N-formyl-L-kynurenine
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
low activity
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
13.5% activity compared to N-formyl-L-kynurenine
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
N-formylanthranilic acid + H2O
formate + anthranilic acid
-
involvement in anthranilate cycle
-
?
