Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.5.1.9: arylformamidase

This is an abbreviated version!
For detailed information about arylformamidase, go to the full flat file.

Word Map on EC 3.5.1.9

Reaction

N-formyl-L-kynurenine
+
H2O
=
formate
+
L-kynurenine

Synonyms

AFMID, Bna7p, FKF, formamidase I, formamidase II, formyl kynurenine formamidase, formylase, formylkynureninase, formylkynurenine formamidase, KFA, KFase, KynB, kynurenine formamidase, kynurine formamidase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.9 arylformamidase

Inhibitors

Inhibitors on EC 3.5.1.9 - arylformamidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-pyridine-2-aldoxime 1'-(pyridine-4-aldoxime) dimethyl ether dichloride
-
HS-3, complete inhibition at 0.5 mM
2-aminoacetophenone
2-pyridine aldoxime
-
31% inhibition at 1 mM
3-hydroxy-DL-kynurenine
-
50% inhibition at 0.2 mM, Ki: 8 mM
3-hydroxykynurenine
-
potent inhibitor
3-pyridine aldoxime O-n-propyl ether
-
43% inhibition at 1 mM
3-pyridine aldoxime O-phenyl ether
-
61% inhibition at 1 mM
acetone
-
inhibition up to 10%, v/v
anthranilic acid
arsenate
-
strong inhibition for formamidase I, slight inhibition for formamidase II at 1 mM
ascorbate
-
50% inhibition at 10 mM
Ba2+
-
strong inhibition at 1 mM
bis(4-nitrophenyl)phosphate
-
slight inhibition at 1 mM after 30 min preincubation
bromphenol blue
-
50% inhibition at 0.024 mM after 5 min preincubation
Carbaryl
-
moderately potent teratogen, Kd: 0.085 mM
diazinon
diazoxon
dichlorvos
-
dicrotophos
diethyl dicarbonate
-
90% inhibition at 0.5 mM
diethyl-(4-nitrophenyl)-phosphate
diisopropylfluorophosphate
-
complete inhibition at 0.01 mM
Dimethoate
-
dimethyl sulfoxide
-
inhibition up to 10%, v/v
dioxane
-
inhibition up to 10%, v/v
EDTA
-
0.1 mM, complete inactivation
ethylpirimiphos
-
Fe2+
-
31% inhibition only for formamidase II at 1 mM
hydrosulfite
-
strong inhibition at 1 mM
iodoacetamide
-
slight inhibition at 1 mM for both formamidases I and II
isoleucine
-
19% inhibition at 20 mM
L-kynurenine
L-tryptophan
-
non-competitive inhibition, Ki: 5.24 mM
methamidophos
-
methionine
-
20% inhibition at 20 mM
methyl parathion
O,O-dimethyl-O-4-nitrophenyl phosphorothioate
methyl-triphenyl phosphonium bromide
-
-
methylchlorpyriphos
-
methylparathion
-
methylpirimiphos
-
Mg2+
-
moderate inhibition at 1 mM
Monocrotophos
N,N-Dimethylformamide
-
inhibition up to 10%, v/v
N-acetylanthranilic acid
-
15% inhibition at 6.7 mM
N-bromosuccinimide
N-ethyloxycarbonyl-2-ethyloxy-1,2-dihydroquinoline
-
53% inhibition at 1 mM
N-formyl-o-aminotoluene
-
45% inhibition at 6.7 mM
Na-bisulfite
Na-Metaarsenite
Na2S2O4
NaAsO2
NaCN
-
31% inhibition at 5 mM
NaHSO3
NH2OH*HCl
-
14% inhibition at 3 mM
O,O-Diethyl-O-(4-nitrophenyl)phosphate
-
E600, complete inhibition at 1 mM
o-aminobenzamidine
-
62% inhibition at 0.5 mM
p-chloromercuribenzoate
-
strong inhibition at 0.1 mM for both formamidases I and II
p-hydroxymercuribenzoate
-
complete inhibition at 1 mM
p-nitrophenyldiethyl phosphoric acid
-
92% inhibition at 10 mM
phenyl saligenin cyclic phosphate
-
Kd: 0.00083 mM
phenylalanine
phenylmethylsulfonyl fluoride
Phosphamidon
-
PMSF
binding structure analysis, overview
Salicyl aldoxime
-
71% inhibition at 1 mM
tetraethyl diphosphate
-
Kd: 67 mM
tetraheptylammonium bromide
-
94% inhibition at 2.5 mM
tetrahexylammonium bromide
-
56% inhibition at 5 mM
tetraoctylammoniumbromide
-
94% inhibition at 2.5 mM
tetraphenyl phosphonium bromide
-
22% inhibition at 5 mM
threonine
-
19% inhibition at 20 mM
trimethyl-n-decylammonium bromide
-
65% inhibition at 5 mM
trimethyl-n-decylammonium chloride
-
65% inhibition at 5 mM
trimethyl-n-hexadecylammonium bromide
-
100% inhibition at 5 mM
trimethylhexadecylammonium chloride
-
100% inhibition at 5 mM
trimethylphenylammonium bromide
-
20% inhibition at 5 mM
trimethylphenylammonium chloride
-
20% inhibition at 5 mM
valine
-
slight inhibition at 20 mM
additional information
-