3.5.1.88: peptide deformylase
This is an abbreviated version!
For detailed information about peptide deformylase, go to the full flat file.
Word Map on EC 3.5.1.88
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3.5.1.88
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actinonin
-
medicine
-
n-formylated
-
deformylation
-
eubacteria
-
hydroxamic
-
drug development
-
formyltransferase
-
oxazolidinone
-
catarrhalis
-
linezolid
-
moraxella
-
hexxh
-
biotechnology
-
synthesis
-
agriculture
-
molecular biology
-
analysis
- 3.5.1.88
- actinonin
- medicine
-
n-formylated
-
deformylation
- eubacteria
-
hydroxamic
- drug development
-
formyltransferase
-
oxazolidinone
- catarrhalis
- linezolid
- moraxella
-
hexxh
- biotechnology
- synthesis
- agriculture
- molecular biology
- analysis
Reaction
Synonyms
AtDEF1.1, AtDEF1.2, AtDEF2, AtPDF1A, AtPDF1B, AtPDF1Bt, AtPDF2, BbPDF, BcPDF, BcPDF2, DEF, Def1, DEF2, deformylase, peptide N-formylmethionine, EC 3.5.1.27, EcPDF, ECPDF1B, EfPDF, HpPDF, HsPDF, hydrolase, aminoacyl-transfer ribonucleate, LiPDF, mPDF, Ni-peptide deformylase, PDF, PDF-1, PDF-2, PDF1A, PDF1B, PDF2, PdfA, PdfB, PdfC, peptide deformylase, peptide deformylase 1, peptide deformylase 1A, peptide deformylase 1B, peptide deformylase 2, Pf PDF, PfPDF, Polypeptide deformylase, SaPDF, sPDF, TbPDF1, TbPDF2, type I PDF, type II PDF, type II peptide deformylase, Vp 16 PDF1B, Vp16 PDF, Vp16T, XOO1075, XoPDF
ECTree
3.5.1.88 peptide deformylaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 3.5.1.88 - peptide deformylase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
formyl-L-methionyl peptide + H2O
formate + L-methionyl peptide
-
peptide deformylase catalyzes the removal of N-terminal formyl groups from nascent ribosome-synthesized polypeptides
-
-
?
formyl-L-methionyl peptide + H2O
formate + L-methionyl peptide
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
?
formyl-L-methionyl peptide + H2O
formate + methionyl peptide
-
-
-
-
?
N-formyl-L-methionine polypeptide + H2O
formate + methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine polypeptide + H2O
formate + methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine polypeptide + H2O
formate + methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine polypeptide + H2O
formate + methionine-polypeptide
-
-
-
?
N-formyl-L-methionine polypeptide + H2O
formate + methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
essential role in protein processing in plastids
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
deformylase is likely to play an essential role in the chloroplast
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
deformylation required for methionine aminopeptidase activity in eubacteria, highly specific
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
requires at least a dipeptide as substrate, increasing activity with increasing peptide length until it reaches the tetrapeptide
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
deformylation required for methionine aminopeptidase activity in eubacteria, highly specific
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
the enzyme is involved in maturation of proteins by cleaving the N-formyl group from N-blocked methionine polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
the enzyme is requiredfor the removal of the formyl group at the N-terminus of nascent polypeptide chains
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
posttranslational deformylation of N-formyl-Met-polypeptide
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
deformylation required for methionine aminopeptidase activity in eubacteria, highly specific
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
deformylation required for methionine aminopeptidase activity in eubacteria, highly specific
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
Thermotoga maritima MSB8 / DSM 3109 / ATCC 43589
involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides
-
-
?
N-formyl-L-methionine-polypeptide + H2O
formate + L-methionine-polypeptide
-
-
-
?
additional information
?
-
catalyzes the deformylation of nascent peptides in bacteria
-
-
?
additional information
?
-
-
catalyzes the deformylation of nascent peptides in bacteria
-
-
?
additional information
?
-
the removal of the formyl group from formylated methionine residues is facilitated by the action of peptide deformylase
-
-
?
additional information
?
-
-
the removal of the formyl group from formylated methionine residues is facilitated by the action of peptide deformylase
-
-
?
additional information
?
-
the formyl moiety of newly synthesized peptides is removed by peptide deformylase
-
-
?
additional information
?
-
-
the formyl moiety of newly synthesized peptides is removed by peptide deformylase
-
-
?
additional information
?
-
catalyzes the removal of the N-formyl group from the N-terminus of newly synthesized proteins
-
-
?
additional information
?
-
-
catalyzes the removal of the N-formyl group from the N-terminus of newly synthesized proteins
-
-
?
additional information
?
-
-
peptide deformylase is involved in the deformylation of the N-formyl group of newly synthesized polypeptides during protein synthesis
-
-
?
additional information
?
-
Mycobacterium tuberculosis H37Ra / ATCC 25177
-
peptide deformylase is involved in the deformylation of the N-formyl group of newly synthesized polypeptides during protein synthesis
-
-
?
additional information
?
-
catalyzes the removal of the N-formyl group from the N-terminus of newly synthesized proteins
-
-
?
additional information
?
-
the formyl group is removed from nascent proteins by peptide deformylase
-
-
?
additional information
?
-
the formyl group is removed from nascent proteins by peptide deformylase
-
-
?
additional information
?
-
-
the formyl group is removed from nascent proteins by peptide deformylase
-
-
?
additional information
?
-
-
peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis
-
-
?
additional information
?
-
Staphylococcus enteridis
-
peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis
-
-
?
additional information
?
-
-
peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis
-
-
?
additional information
?
-
Staphylococcus non-hemolyticus
-
peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis
-
-
?
additional information
?
-
-
peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis
-
-
?
additional information
?
-
-
TbPDF1 is essential for normal growth. TbPDF1 is required for oxidative but not for mitochondrial substrate-level phosphorylation
-
-
?
additional information
?
-
-
TbPDF2 does neither affect growth on standard medium nor oxidative phosphorylation. A reduced level of TbPDF2 slows down growth in a medium that selects for highly efficient oxidative phosphorylation
-
-
?
additional information
?
-
-
catalyzes the removal of the N-formyl group from the N-terminus of newly synthesized polypeptides
-
-
?
