3.5.1.88: peptide deformylase
This is an abbreviated version!
For detailed information about peptide deformylase, go to the full flat file.
Word Map on EC 3.5.1.88
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3.5.1.88
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actinonin
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medicine
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n-formylated
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deformylation
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eubacteria
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hydroxamic
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drug development
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formyltransferase
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oxazolidinone
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catarrhalis
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linezolid
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moraxella
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hexxh
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biotechnology
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synthesis
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agriculture
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molecular biology
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analysis
- 3.5.1.88
- actinonin
- medicine
-
n-formylated
-
deformylation
- eubacteria
-
hydroxamic
- drug development
-
formyltransferase
-
oxazolidinone
- catarrhalis
- linezolid
- moraxella
-
hexxh
- biotechnology
- synthesis
- agriculture
- molecular biology
- analysis
Reaction
Synonyms
AtDEF1.1, AtDEF1.2, AtDEF2, AtPDF1A, AtPDF1B, AtPDF1Bt, AtPDF2, BbPDF, BcPDF, BcPDF2, DEF, Def1, DEF2, deformylase, peptide N-formylmethionine, EC 3.5.1.27, EcPDF, ECPDF1B, EfPDF, HpPDF, HsPDF, hydrolase, aminoacyl-transfer ribonucleate, LiPDF, mPDF, Ni-peptide deformylase, PDF, PDF-1, PDF-2, PDF1A, PDF1B, PDF2, PdfA, PdfB, PdfC, peptide deformylase, peptide deformylase 1, peptide deformylase 1A, peptide deformylase 1B, peptide deformylase 2, Pf PDF, PfPDF, Polypeptide deformylase, SaPDF, sPDF, TbPDF1, TbPDF2, type I PDF, type II PDF, type II peptide deformylase, Vp 16 PDF1B, Vp16 PDF, Vp16T, XOO1075, XoPDF
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KCat KM Value
KCat KM Value on EC 3.5.1.88 - peptide deformylase
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63
N-formyl-L-Met-L-Ala-L-Ser
Co2+-substituted PDF-1, in 50 mM HEPES, pH 7.5, at 37°C
0.08
pH 4.5, 37°C, recombinant enzyme with bound Zn2+
0.867
formyl-Met-Ala-Ser
pH 7.5, 37°C, recombinant enzyme with bound Zn2+, Zn-Vp16 PDF1B
5.3
formyl-Met-Ala-Ser
pH 7.5, 37°C, recombinant enzyme with bound Ni2+, Ni-Vp16 PDF1B
170
formyl-Met-Ala-Ser
pH 4.5, 37°C, recombinant enzyme with bound Ni2+
0.1
pH 7.0, 30°C, recombinant enzyme mutant C130M/V63C
0.5
N-formyl-Met-Ala
pH 7.0, 30°C, recombinant wild-type enzyme
0.7
N-formyl-Met-Ala
pH 7.0, 30°C, recombinant enzyme mutant M145C
3
N-formyl-Met-Ala
pH 7.0, 30°C, recombinant wild-type enzyme
0.26
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mutant enzyme G49C, in 20 mM phosphate buffer, pH 7.4, temperature not specified in the publication
0.795
N-formyl-Met-Ala-Ser
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mutant enzyme G151A, in 20 mM phosphate buffer, pH 7.4, temperature not specified in the publication
0.842
N-formyl-Met-Ala-Ser
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wild type enzyme, in 20 mM phosphate buffer, pH 7.4, temperature not specified in the publication
0.948
N-formyl-Met-Ala-Ser
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mutant enzyme F134C/R137S, at pH 7.2 and 37°C
1.786
N-formyl-Met-Ala-Ser
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mutant enzyme G151D, in 20 mM phosphate buffer, pH 7.4, temperature not specified in the publication