3.5.1.69: glycosphingolipid deacylase
This is an abbreviated version!
For detailed information about glycosphingolipid deacylase, go to the full flat file.
Reaction
Synonyms
deacylase, glycosphingolipid ceramide, glycosphingolipid ceramide deacylase, PS_SCD, SA_SCD, SCDase, sphingolipid ceramide N-acylase, sphingolipid ceramide N-deacylase
ECTree
3.5.1.69 glycosphingolipid deacylaseAdvanced search results
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results (Inhibitors
Inhibitors on EC 3.5.1.69 - glycosphingolipid deacylase
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
Ca2+
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme
Co2+
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme
deoxycholic acid
complete inhibition of the hydrolytic and synthetic activity
dimethoxyethane
addition of 5% of DME strongly promoted the activity, further increasing the DME concentrations progressively inhibited synthetic activity
DMSO
low concentrations of DMSO, up to a maximum at 10%, enhance synthetic activity, while higher concentrations inhibit
Fe2+
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme
Mg2+
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme
Ni2+
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme
taurodeoxycholate
complete inhibition of the hydrolytic and synthetic activity
Triton X-100
activates the hydrolytic reaction, best at 0.5% w/v, but inhibits the synthetic reaction
Cu2+
inhibits the hydrolytic activity and the synthetic activity of the enzyme
Mn2+
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme
Zn2+
inhibits the hydrolytic activity and the synthetic activity of the enzyme
