3.5.1.52: peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase

This is an abbreviated version!
For detailed information about peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase, go to the full flat file.

Word Map on EC 3.5.1.52

3.5.1.52

deglycosylation

n-glycans

lectin

glycopeptides

sialic

endoglycosidase

mannose

neuraminidase

o-linked

tunicamycin

sialylated

n-acetylglucosamine

asparagine-linked

fucose

glcnac

concanavalin

high-mannose

agglutinin

complex-type

fucosylated

sialidase

glycoforms

endo-beta-n-acetylglucosaminidase

biantennary

glycomics

asn-linked

high-mannose-type

glycoproteomic

n-acetyllactosamine

almond

tetraantennary

2-aminopyridine

meningosepticum

n-glycoproteins

endo-beta-galactosidase

fetuin

analysis

keratanase

permethylated

3hglucosamine

hybrid-type

mannose-type

oligomannosidic

synthesis

hydrazinolysis

man9glcnac2

trifluoromethanesulfonic

pyridylaminated

high-ph

oligomannose

retrotranslocation

neu5ac

Reaction

Manalpha(1-6)(Xylbeta(1-2))Manbeta(1-4)GlcNAcbeta(1-4)(Fucalpha(1-3))GlcNAc-Asn-Asp-Glu-Ser-Ser

Manalpha(1-6)(Xylbeta(1-2))Manbeta(1-4)GlcNAcbeta(1-4)(Fucalpha(1-3))GlcNAc

Synonyms

acid PNGase M, acidic peptide:N-glycanase, acidic PNGase, aPNGase, At3g14920, At5g05480, AtPNG1, DDB0189828, EC 3.2.2.18, glycoamidase, glycopeptidase, glycopeptide N-glycosidase, jackbean glycopeptidase, L-929 PNGase, MPng1, N-glycanase, N-glycosidase F, N-oligosaccharide glycopeptidase, Ncpng1, neutral PNGase M, Ngly1, peptide N-glycanase, peptide N-glycosidase, peptide N-glycosidase F, peptide N4(N-acetyl-glucosaminyl)asparagine amidase, peptide-N-(N-acetyl-beta-glucosaminyl) asparagine amidase F, peptide-N-glycanase, peptide-N-glycosidase F, peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F, peptide-N4-(N-acetyl-beta-glucosaminyl) asparagine amidase, peptide: N-glycanase, peptide: N-glycosidase, peptide:N-glycanase, peptide:N-glycanase homolog, peptide:N-glycosidase, peptidyl N-glycanase F, PGNase, PNG-1, PNG1, Png1p, PNGase, PNGase A, PNGase A-like enzyme, PNGase At, PNGase F, PNGase F-II, PNGase H+, PNGase J, PNGase Os, PNGase Se, PNGase Yl, PNGase-A, PNGaseF, Pngl, SpPNGase, TGc domain-containing protein, yeast peptide: N-glycanase, YPng, YPng1

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.1.52 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase

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Results	in table
3	Activating Compound
1546	AA Sequence
5	Application
1	CAS Registry Number
39	Cloned(Commentary)
6	Crystallization (Commentary)
393	Disease/ Diagnostics
51	General Information
2	General Stability
8	IC50 Value
92	Inhibitors
10	KM Value [mM]
51	Localization
19	Metals/Ions
20	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
121	Organism
1	Oxidation Stability
16	PDB ID
36	pH Optimum
16	pH Range
4	Posttranslational Modification
76	Protein Variants
29	Purification (Commentary)
6	Reaction
4	Reaction Type
119	Reference
52	Source Tissue
6	Specific Activity [micromol/min/mg]
4	Storage Stability
157	Substrates and Products (Substrate)
24	Subunits
226	Synonyms
1	Systematic Name
19	Temperature Optimum [°C]
7	Temperature Range [°C]
5	Temperature Stability [°C]

Reference

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Reference on EC 3.5.1.52 - peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase

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171678

Tarentino, A.L.; Plummer, T.H.

Peptide-N4-(N-acetyl-beta-glucosaminyl) asparagine amidase and endo-beta-N-acetylglucosaminidase from Flavobacterium meningosepticum

Methods Enzymol.

138

770-778

1987

Elizabethkingia meningoseptica

3110550

288909

Makino, M.; Kojima, T.; Ohgushi, T.; Yamashina, I.

Studies on enzymes acting on glycopeptides

J. Biochem.

186-192

1968

Cavia porcellus, Rattus norvegicus, Sus scrofa

5669921

288910

Takahashi, N.

Demonstration of a new amidase acting on glycopeptides

Biochem. Biophys. Res. Commun.

1194-1201

1977

Prunus amygdalus var. dulcis

901470

288911

Takahashi, N.; Nishibe, H.

Some characteristics of a new glycopeptidase acting on aspartylglycosylamine linkages

J. Biochem.

1467-1473

1978

Prunus amygdalus var. dulcis

738997

288912

Ishihara, H.; Takahashi, N.; Oguri, S.; Tejima, S.

Complete structure of the carbohydrate moiety of stem bromelain. An application of the almond glycopeptidase for structural studies of glycopeptides

J. Biol. Chem.

254

10715-10719

1979

Prunus amygdalus var. dulcis

500606

288913

Takahashi, N.; Nishibe, H.

Almond glycopeptidase acting on aspartylglycosylamine linkages. Multiplicity and substrate specificity

Biochim. Biophys. Acta

657

457-467

1981

Prunus amygdalus var. dulcis

7213757

288914

Nishibe, H.; Takahashi, N.

The release of carbohydrate moieties from human fibrinogen by almond glycopeptidase without alteration in fibrinogen clottability

Biochim. Biophys. Acta

661

274-279

1981

Prunus amygdalus var. dulcis

7295738

288915

Takahashi, N.; Shimizu, S.; Yamada, K.

Asparagine-linked oligosaccharides in human placenta and umbilical cord as demonstrated by almond glycopeptidase

FEBS Lett.

146

139-142

1982

Prunus amygdalus var. dulcis

7140973

288916

Takahashi, N.; Toda, H.; Nishibe, H.; Yamamoto, K.

Isolation and characterization of Taka-amylase A apoprotein deglycosylated by digestion with almond glycopeptidase immobilized on Sepharose

Biochim. Biophys. Acta

707

236-242

1982

Prunus amygdalus var. dulcis

6182919

288917

Sugiyama, K.; Ishihara, H.; Tejima, S.; Takahashi, N.

Demonstration of a new glycopeptidase, from jack-bean meal, acting on aspartylglucosylamine linkages

Biochem. Biophys. Res. Commun.

112

155-160

1983

Canavalia ensiformis

6838602

288918

Tomiya, N.; Kurono, M.; Ishihara, H.; Tejima, S.; Endo, S.; Arata, Y.; Takahashi, N.

Structural analysis of N-linked oligosaccharides by a combination of glycopeptidase, exoglycosidases, and high-performance liquid chromatography

Anal. Biochem.

163

489-499

1987

Canavalia ensiformis

3661998

288919

Plummer Jr., T.H.; Phelan, A.W.; Tarentino, A.L.

Detection and quantification of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidases

Eur. J. Biochem.

163

167-173

1987

Canavalia ensiformis, Lens culinaris, Pisum sativum, Prunus amygdalus var. dulcis, Triticum aestivum

2434326

288921

Barsomian, G.D.; Johnson, T.L.; Borowski, M.; Denman, J.; Ollington, J.F.; Hirani, S.; McNeilly, D.S.; Rasmussen, J.R.

Cloning and expression of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F in Escherichia coli

J. Biol. Chem.

265

6967-6872

1990

Elizabethkingia meningoseptica

2182635

288922

Suzuki, T.; Seko, A.; Kitajima, K.; Inoue, Y.; Inoue, S.

Purification and enzymatic properties of peptide:N-glycanase from C3H mouse-derived L-929 fibroblast cells

J. Biol. Chem.

269

17611-17618

1994

Elizabethkingia meningoseptica, Oryzias latipes, Mus musculus

8021270

288923

Suzuki, T.; Kitajima, K.; Inoue, S.; Inoue, Y.

Does an animal peptide N:glycanase have the dual role as an enzyme and a carbohydrate binding protein?

Glycoconj. J.

469-476

1994

Elizabethkingia meningoseptica, Oryzias latipes, Mus musculus, Prunus amygdalus var. dulcis

7535137

288924

Kuhn, P.; Tarentino, A.L.; Plummer, T.H.; Van Roey, P.

Crystal structure of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F at 2.2-A resolution

Biochemistry

11699-11706

1994

Elizabethkingia meningoseptica

7918386

288925

Lhernould, S.; Karamanos, Y.; Lerouge, P.; Morvan, H.

Characterization of the peptide-N4-(N-acetylglucosaminyl)asparagine amidase (PNGase Se) from Silene alba cells

Glycoconj. J.

94-98

1995

Silene latifolia subsp. alba

7795418

288926

Kitajima, K.; Suzuki, T.; Kouchi, Z.; Inoue, S.; Inoue, Y.

Identification and distribution of peptide:N-glycanase (PNGase) in mouse organs

Arch. Biochem. Biophys.

319

393-401

1995

Mus musculus

7786020

288927

Suzuki, T.; Kitajima, K.; Inoue, Y.; Inoue, S.

Carbohydrate-binding property of peptide:N-glycanase from mouse fibroblast L-929 cells as evaluated by inhibition and binding experiments using various oligosaccharides

J. Biol. Chem.

270

15181-15186

1995

Elizabethkingia meningoseptica, Mus musculus, Prunus amygdalus var. dulcis

7797502

288928

Weng, S.; Spiro, R.G.

Demonstration of a peptide:N-glycanase in the endoplasmatic reticulum of rat liver

Biochem. J.

322

655-661

1997

Rattus norvegicus

9065790

288929

Ftouhi-Paquin, N.; Hauer, C.R.; Stack, R.F.; Tarentino, A.L.; Plummer Jr., T.H.

Molecular cloning, primary structur, and properties of a new glycoamidase from the fungus Aspergillus tubigensis

J. Biol. Chem.

272

22960-22965

1997

Aspergillus tubingensis

9312552

288930

Altmann, F.; Paschinger, K.; Dalik, T.; Vorauer, K.

Characterization of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A and its N-glycans

Eur. J. Biochem.

252

118-123

1998

Prunus amygdalus var. dulcis

9523720

288931

Sheldon, P.S.; Keen, J.N.; Bowles, D.J.

Purification and characterization of N-glycanase, a concanavalin A binding protein from jackbean (Canavalia ensiformis)

Biochem. J.

330

13-20

1998

Canavalia ensiformis

288932

Suzuki, T.; Park, H.; Kitajima, K.; Lennarz, W.J.

Peptides glycosylated in the endoplasmatic reticulum of yeast are subsequently deglycosylated by a soluble peptide:N-glycanase activity

J. Biol. Chem.

273

21526-21530

1998

Saccharomyces cerevisiae

9705282

288933

Seko, A.; Kitajima, K.; Iwamatsu, T.; Inoue, Y.; Inoue, S.

Identification of two dicrete peptide:N-glycanases in Oryzias latipes during embryogenesis

Glycobiology

887-895

1999

Oryzias latipes

10460830

288934

Chang, T.; Meng-Chiang, K.; Inoue, S.; Inoue, Y.

Developmentally regulated expression of a peptide:N-glycanase during germination of rice seeds (Oryza sativa) and its purification and characterization

J. Biol. Chem.

275

129-134

2000

Oryza sativa

10617595

649758

Chantret, I.; Frenoy, J.P.; Moore, S.E.H.

Free-oligosaccharide control in the yeast Saccharomyces cerevisiae: roles for peptide:N-glycanase (Png1p) and vacuolar mannosidase (Ams1p)

Biochem. J.

373

901-908

2003

Saccharomyces cerevisiae

12723970

651002

Hirsch, C.; Misaghi, S.; Blom, D.; Pacold, M.E.; Ploegh, H.L.

Yeast N-glycanase distinguishes between native and non-native glycoproteins

EMBO Rep.

201-206

2004

Saccharomyces cerevisiae

14726951

651226

Suzuki, T.; Park, H.; Lennarz, W.J.

Cytoplasmic peptide:N-glycanase (PNGase) in eukaryotic cells: occurrence, primary structure, and potential functions

FASEB J.

635-641

2002

Saccharomyces cerevisiae

11978727

652230

Katiyar, S.; Suzuki, T.; Balgobin, B.J.; Lennarz, W.J.

Site-directed mutagenesis study of yeast peptide: N-glycanase. Insight into the reaction mechanism of deglycosylation

J. Biol. Chem.

277

12953-12959

2002

Saccharomyces cerevisiae

11812789

667394

Biswas, S.; Katiyar, S.; Li, G.; Zhou, X.; Lennarz, W.J.; Schindelin, H.

The N-terminus of yeast peptide: N-glycanase interacts with the DNA repair protein Rad23

Biochem. Biophys. Res. Commun.

323

149-155

2004

Saccharomyces cerevisiae

15351714

668192

MIsaghi, S.; Korbel, G.A.; Kessler, B.; Spooner, E.; Ploegh, H.L.

Z-VAD-fmk inhibits peptide:N-glycanase and may result in ER stress

Cell Death Differ.

163-165

2006

Saccharomyces cerevisiae

16003388

668234

Misaghi, S.; Pacold, M.; Blom, D.; Ploegh, H.L.; Korbel, G.A.

Using a small molecule inhibitor of peptide:N-glycanaseto probe its role in glycoprotein turnover

Chem. Biol.

1677-1687

2004

Saccharomyces cerevisiae, Homo sapiens, Mus musculus

15610852

668402

Blom, D.; Hirsch, C.; Stern, P.; Tortorella, D.; Ploegh, H.L.

A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised

EMBO J.

650-658

2004

Homo sapiens

14749736

668438

Jeong, H.Y.; Lee, J.Y.; Park, T.H.

Specificity of enzymatic in vitro glycosylation by PNGase F: a comparison of enzymatic and non-enzymatic glycosylation

Enzyme Microb. Technol.

587-591

2004

Elizabethkingia meningoseptica

668628

Joshi, S.; Katiyar, S.; Lennarz, W.J.

Misfolding of glycoproteins is a prerequisite for peptide; N-glycanase mediated deglycosylation

FEBS Lett.

579

823-826

2005

Saccharomyces cerevisiae

15670854

669446

Zhao, G.; Zhou, X.; Wang, L.; Li, G.; Kisker, C.; Lennarz, W.J.; Schindelin, H.

Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways

J. Biol. Chem.

281

13751-13761

2006

Mus musculus

16500903

669486

Allen, M.D.; Buchberger, A.; Bycroft, M.

The PUB domain functions as a p97 binding module in human peptide N-glycanase

J. Biol. Chem.

281

25502-25508

2006

Homo sapiens

16807242

669579

Kim, I.; Ahn, J.; Liu, C.; Tanabe, K.; Apocadaca, J.; Suzuki, T.; Rao, H.

The Png1-Rad23 complex regulates glycoprotein turnover

J. Cell Biol.

172

211-219

2006

Saccharomyces cerevisiae

16401726

669733

Altrich-VanLith, M.L.; Ostankovitch, M.; Polefrone, J.M.; Mosse, C.A.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H.

Processing of a class I-restricted epitope from tyrosinase requires peptide N-glycanase and the cooperative action of endoplasmic reticulum aminopeptidase 1 and cytosolic protease

J. Immunol.

177

5440-5450

2006

Homo sapiens

17015730

670678

Li, G.; Zhou, X.; Zhao, G.; Schindelin, H.; Lennarz, W.J.

Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome

Proc. Natl. Acad. Sci. USA

102

15809-15814

2005

Mus musculus

16249333

670704

Li, G.; Zhao, G.; Zhou, X.; Schindelin, H.; Lennarz, W.J.

The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor

Proc. Natl. Acad. Sci. USA

103

8348-8353

2006

Mus musculus

16709668

670850

Rathbone, E.; Electricwala, A.; Wright, I.

PNGase F enzyme: efficient N-deglycosylation in glycoprotein analysis

Proteomics

14-15

2004

Elizabethkingia meningoseptica

677415

Faugeron, C.; Mollet, J.; Karamanos, Y.; Morvan, H.

Activities of de-N-glycosylation are ubiquitously found in tomato plant

Acta Physiol. Plant.

557-565

2006

Solanum lycopersicum

684119

Wang, S.; Wang, P.G.; Qi, Q.

Influence of substrate conformation on the deglycosylation of ribonuclease B by recombinant yeast peptide:N-glycanase

Acta Biochim. Biophys. Sin. (Shanghai)

8-14

2007

Saccharomyces cerevisiae

17213953

684394

Mueller, R.; Marchetti, M.; Kratzmeier, M.; Elgass, H.; Kuschel, M.; Zenker, A.; Allmaier, G.

Comparison of planar SDS-PAGE, CGE-on-a-chip, and MALDI-TOF mass spectrometry for analysis of the enzymatic de-N-glycosylation of antithrombin III and coagulation factor IX with PNGase F

Anal. Bioanal. Chem.

389

1859-1868

2007

Elizabethkingia meningoseptica

17879089

684851

Suzuki, T.; Tanabe, K.; Hara, I.; Taniguchi, N.; Colavita, A.

Dual enzymatic properties of the cytoplasmic peptide: N-glycanase in C. elegans

Biochem. Biophys. Res. Commun.

358

837-841

2007

Caenorhabditis elegans

17509531

684873

Yamaguchi, Y.; Hirao, T.; Sakata, E.; Kamiya, Y.; Kurimoto, E.; Yoshida, Y.; Suzuki, T.; Tanaka, K.; Kato, K.

Fbs1 protects the malfolded glycoproteins from the attack of peptide:N-glycanase

Biochem. Biophys. Res. Commun.

362

712-716

2007

Mus musculus

17720138

684908

Xin, F.; Wang, S.; Song, L.; Liang, Q.; Qi, Q.

Molecular identification and characterization of peptide: N-glycanase from Schizosaccharomyces pombe

Biochem. Biophys. Res. Commun.

368

907-912

2008

Schizosaccharomyces pombe

18279662

685226

Blanchard, V.; Frank, M.; Leeflang, B.R.; Boelens, R.; Kamerling, J.P.

The structural basis of the difference in sensitivity for PNGase F in the de-N-glycosylation of the native bovine pancreatic ribonucleases B and BS

Biochemistry

3435-3446

2008

Elizabethkingia meningoseptica

18293928

686438

Su, Y.; Zhang, H.; Gu, L.; Chen, M.; Xiao, M.; Wang, P.G.; Qi, Q.

Engineered yeast with PNGase F on cell surface for releasing of N-glycans from glycoproteins

Enzyme Microb. Technol.

1496-1502

2007

Elizabethkingia meningoseptica

686967

Hagihara, S.; Miyazaki, A.; Matsuo, I.; Tatami, A.; Suzuki, T.; Ito, Y.

Fluorescently labeled inhibitor for profiling cytoplasmic peptide:N-glycanase

Glycobiology

1070-1076

2007

Saccharomyces cerevisiae

17640972

687444

Kato, T.; Kawahara, A.; Ashida, H.; Yamamoto, K.

Unique peptide:N-glycanase of Caenorhabditis elegans has activity of protein disulphide reductase as well as of deglycosylation

J. Biochem.

142

175-181

2007

Caenorhabditis elegans (Q9TW67), Caenorhabditis elegans

17522090

687514

Suzuki, T.; Hara, I.; Nakano, M.; Zhao, G.; Lennarz, W.J.; Schindelin, H.; Taniguchi, N.; Totani, K.; Matsuo, I.; Ito, Y.

Site-specific labeling of cytoplasmic peptide:N-glycanase by N,N-diacetylchitobiose-related compounds

J. Biol. Chem.

281

22152-22160

2006

Saccharomyces cerevisiae

16740630

688656

Ghesquiere, B.; Van Damme, J.; Martens, L.; Vandekerckhove, J.; Gevaert, K.

Proteome-wide characterization of N-glycosylation events by diagonal chromatography

J. Proteome Res.

2438-2447

2006

Elizabethkingia meningoseptica

16944957

688824

Tanabe, K.; Lennarz, W.J.; Suzuki, T.

A cytoplasmic peptide: N-glycanase

Methods Enzymol.

415

46-55

2006

Elizabethkingia meningoseptica

17116467

689305

Witte, M.D.; Descals, C.V.; de Lavoir, S.V.; Florea, B.I.; van der Marel, G.A.; Overkleeft, H.S.

Bodipy-VAD-Fmk, a useful tool to study yeast peptide N-glycanase activity

Org. Biomol. Chem.

3690-3697

2007

Saccharomyces cerevisiae

17971999

689541

Diepold, A.; Li, G.; Lennarz, W.J.; Nuernberger, T.; Brunner, F.

The Arabidopsis AtPNG1 gene encodes a peptide: N-glycanase

Plant J.

94-104

2007

Arabidopsis thaliana

17666024

689785

Zhao, G.; Zhou, X.; Wang, L.; Li, G.; Schindelin, H.; Lennarz, W.J.

Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation

Proc. Natl. Acad. Sci. USA

104

8785-8790

2007

Mus musculus (Q9JI78)

17496150

690063

Suzuki, T.

Cytoplasmic peptide:N-glycanase and catabolic pathway for free N-glycans in the cytosol

Semin. Cell Dev. Biol.

762-769

2007

Arabidopsis thaliana, Saccharomyces cerevisiae, Mus musculus

17950635

696339

Fahrenkrug, J.; Falktoft, B.; Georg, B.; Rask, L.

N-linked deglycosylated melanopsin retains its responsiveness to light

Biochemistry

5142-5148

2009

Rattus norvegicus (Q5XI55)

19413349

696389

Unal, E.S.; Zhao, R.; Qiu, A.; Goldman, I.D.

N-linked glycosylation and its impact on the electrophoretic mobility and function of the human proton-coupled folate transporter (HsPCFT)

Biochim. Biophys. Acta

1778

1407-1414

2008

Homo sapiens

18405659

698128

Zhao, G.; Li, G.; Zhou, X.; Matsuo, I.; Ito, Y.; Suzuki, T.; Lennarz, W.J.; Schindelin, H.

Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase

Glycobiology

118-125

2009

Saccharomyces cerevisiae (Q02890), Saccharomyces cerevisiae

18854368

711705

Gefter, J.V.; Shaufl, A.L.; Fink, M.P.; Delude, R.L.

Comparison of distinct protein isoforms of the receptor for advanced glycation end-products expressed in murine tissues and cell lines

Cell Tissue Res.

337

79-89

2009

Elizabethkingia meningoseptica

19415334

712451

Maerz, S.; Funakoshi, Y.; Negishi, Y.; Suzuki, T.; Seiler, S.

The Neurospora peptide:N-glycanase ortholog PNG1 is essential for cell polarity despite its lack of enzymatic activity

J. Biol. Chem.

285

2326-2332

2010

Saccharomyces cerevisiae, Neurospora crassa

19940117

712830

Habibi-Babadi, N.; Su, A.; de Carvalho, C.E.; Colavita, A.

The N-glycanase png-1 acts to limit axon branching during organ formation in Caenorhabditis elegans

J. Neurosci.

1766-1776

2010

Caenorhabditis elegans (Q9TW67), Caenorhabditis elegans

20130186

713354

Wang, S.; Xin, F.; Liu, X.; Wang, Y.; An, Z.; Qi, Q.; Wang, P.G.

N-terminal deletion of peptide:N-glycanase results in enhanced deglycosylation activity

PLoS ONE

e8335

2009

Saccharomyces cerevisiae, Elizabethkingia meningoseptica, Schizosaccharomyces pombe

20016784

713364

Chantret, I.; Fasseu, M.; Zaoui, K.; Le Bizec, C.; Yaye, H.S.; Dupre, T.; Moore, S.E.

Identification of roles for peptide: N-glycanase and endo-beta-N-acetylglucosaminidase (Engase1p) during protein N-glycosylation in human HepG2 cells

PLoS ONE

e11734

2010

Homo sapiens

20668520

718792

Huang, P.; Chen, C.; Mague, S.D.; Blendy, J.A.; Liu-Chen, L.Y.

A common single nucleotide polymorphism A118G of the mu opioid receptor alters its N-glycosylation and protein stability

Biochem. J.

441

379-386

2012

Elizabethkingia meningoseptica

21864297

718978

Masahara-Negishi, Y.; Hosomi, A.; Della Mea, M.; Serafini-Fracassini, D.; Suzuki, T.

A plant peptide:N-glycanase orthologue facilitates glycoprotein ER-associated degradation in yeast

Biochim. Biophys. Acta

1810

1457-1462

2012

Arabidopsis thaliana

22659524

719506

Kamiya, Y.; Uekusa, Y.; Sumiyoshi, A.; Sasakawa, H.; Hirao, T.; Suzuki, T.; Kato, K.

NMR characterization of the interaction between the PUB domain of peptide:N-glycanase and ubiquitin-like domain of HR23

FEBS Lett.

586

1141-1146

2012

Mus musculus (Q9JI78)

22575648

719759

Hossain, M.; Nakano, R.; Nakamura, K.; Kimura, Y.

Molecular identification and characterization of an acidic peptide:N-glycanase from tomato (Lycopersicum esculentum) fruits

J. Biochem.

147

157-165

2010

Solanum lycopersicum (D0QU16), Solanum lycopersicum

19819901

720808

Funakoshi, Y.; Negishi, Y.; Gergen, J.P.; Seino, J.; Ishii, K.; Lennarz, W.J.; Matsuo, I.; Ito, Y.; Taniguchi, N.; Suzuki, T.

Evidence for an essential deglycosylation-independent activity of PNGase in Drosophila melanogaster

PLoS ONE

e10545

2010

Saccharomyces cerevisiae, Drosophila melanogaster

20479940

733540

Wang, T.; Cai, Z.P.; Gu, X.Q.; Ma, H.Y.; Du, Y.M.; Huang, K.; Voglmeir, J.; Liu, L.

Discovery and characterization of a novel extremely acidic bacterial N-glycanase with combined advantages of PNGase F and A

Biosci. Rep.

e00149

2014

Terriglobus roseus, Terriglobus roseus DSM 18391

25294009

733566

Gosain, A.; Lohia, R.; Shrivastava, A.; Saran, S.

Identification and characterization of peptide: N-glycanase from Dictyostelium discoideum

BMC Biochem.

9-20

2012

Dictyostelium discoideum (Q55FC8), Dictyostelium discoideum, Dictyostelium discoideum NC-4 / ATCC 24697 (Q55FC8)

22682495

734113

Lee, K.J.; Gil, J.Y.; Kim, S.Y.; Kwon, O.; Ko, K.; Kim, D.I.; Kim, D.K.; Kim, H.H.; Oh, D.B.

Molecular characterization of acidic peptide:N-glycanase from the dimorphic yeast Yarrowia lipolytica

J. Biochem.

157

35-43

2015

Yarrowia lipolytica, Yarrowia lipolytica SMS397A

25147194

753034

Uemura, R.; Ogura, M.; Matsumaru, C.; Akiyama, T.; Maeda, M.; Kimura, Y.

Novel assay system for acidic peptide N-glycanase (aPNGase) activity in crude plant extract

Biosci. Biotechnol. Biochem.

1172-1175

2018

Solanum lycopersicum (F8QR42), Prunus dulcis (P81898), Arabidopsis thaliana (Q9FFG6), Arabidopsis thaliana (Q9LKB2), Solanum lycopersicum Micro-Tom (F8QR42), Arabidopsis thaliana Col-0 (Q9FFG6), Arabidopsis thaliana Col-0 (Q9LKB2)

29658432

754027

Suzuki, T.

The cytoplasmic peptide N-glycanase (Ngly1) - basic science encounters a human genetic disorder

J. Biochem.

157

23-34

2015

Oryzias latipes, Neurospora crassa (D1MY48), Schizosaccharomyces pombe (O74739), Saccharomyces cerevisiae (Q02890), Saccharomyces cerevisiae, Dictyostelium discoideum (Q55FC8), Drosophila melanogaster (Q7KRR5), Homo sapiens (Q96IV0), Homo sapiens, Arabidopsis thaliana (Q9FGY9), Mus musculus (Q9JI78), Caenorhabditis elegans (Q9TW67), Schizosaccharomyces pombe ATCC 24843 (O74739), Schizosaccharomyces pombe 972 (O74739), Saccharomyces cerevisiae ATCC 204508 (Q02890)

25398991

754126

Sun, G.; Yu, X.; Bao, C.; Wang, L.; Li, M.; Gan, J.; Qu, D.; Ma, J.; Chen, L.

Identification and characterization of a novel prokaryotic peptide N-glycosidase from Elizabethkingia meningoseptica

J. Biol. Chem.

290

7452-7462

2015

Elizabethkingia meningoseptica (A0A090KI56), Elizabethkingia meningoseptica

25614628