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3.5.1.5: urease

This is an abbreviated version!
For detailed information about urease, go to the full flat file.

Word Map on EC 3.5.1.5

Reaction

Urea
+
H2O
=
CO2
 + 2 NH3

Synonyms

acid urease, Arthritogenic cationic 19 kDa antigen, BPU, canatoxin, embryo-specific soybean urease, Eu1, Eu4, HPU, jack bean urease, JBU, JBURE-II, More, PMU, urea amido hydrolase, Urea amidohydrolase, urease, urease JBURE-IIb, UreC

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.5 urease

Source Tissue

Source Tissue on EC 3.5.1.5 - urease

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
expression of the urease operon is sensitive to the aspartate concentration in milk and to the cell availability of glutamate, glutamine, and ammonium ions
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
additional information
-
optimal pH for urease activity in whole and permeabilized cells and of cell free extracts differs slightly, but is in the range 6.0-7.0. Significant activity is retained at pH 3.0 and 8.0, and, for cell free extracts, at pH 4.0 in the presence of ethanol. Urease production is evaluated in fermentations with pH control (5.25-6.5) and without pH control. Very little urease is produced in absence of urea, which at 5 g/l slows growth significantly in fermentations without pH control, but prevented a decrease in pH below 5.1 and results in higher final biomass. Optimal pH for growth is between 6.0 and 6.5 but specific urease activity is higher for fermentations at low pH at the beginning of the exponential phase. However, a higher total urease activity is obtained at pH 6.0 and 6.5 because of higher biomass
Manually annotated by BRENDA team