3.5.1.49: formamidase
This is an abbreviated version!
For detailed information about formamidase, go to the full flat file.
Word Map on EC 3.5.1.49
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3.5.1.49
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kynurenine
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urease
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2,3-dioxygenase
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n-formyl-l-kynurenine
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2-aminofluorene
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methylotrophus
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methylophilus
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n-formylation
- 3.5.1.49
- kynurenine
- urease
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2,3-dioxygenase
- n-formyl-l-kynurenine
- 2-aminofluorene
- methylotrophus
- methylophilus
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n-formylation
Reaction
Synonyms
acetamidase/formamidase, Amds/fmds, AmiF, AmiF formamidase, BceAmiF, Fmd, formamidase, formamidase AmiF, Formamide amidohydrolase, formamide aminohydrolase, HpyAmiF, TE19
ECTree
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Substrates Products
Substrates Products on EC 3.5.1.49 - formamidase
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REACTION DIAGRAM
acrylamide + H2O
acrylic acid + NH3
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very low activity
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?
acetic acid + NH3
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very low activity
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?
butyric acid + NH3
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very low activity
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?
formamide + H2O
formate + NH3
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from AmiF gene, that exclusively hydrolyzes formamide, involved in nitrogen metabolism
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?
formamide + H2O
formate + NH3
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from AmiE gene, very low activity
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?
formamide + H2O
formate + NH3
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source of nitrogen for growth and contribution to energy economy of the cell
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propionic acid + NH3
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very low activity
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?
?
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propionamide, butyramide, isobutyramide, alaninamide, leucinamide, glycinamide, and urea are not recognized as substrates
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additional information
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propionamide, butyramide, isobutyramide, alaninamide, leucinamide, glycinamide, and urea are not recognized as substrates
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?
additional information
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3D structure study is built by homology modeling and catalytic mechanism study
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additional information
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formamidase shows no activity with nicotinamide
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?