3.5.1.42: nicotinamide-nucleotide amidase

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For detailed information about nicotinamide-nucleotide amidase, go to the full flat file.

Reaction

Synonyms

AtCinA, CinA, nicotinamide mononucleotide amidohydrolase, nicotinamide mononucleotide deamidase, nicotinamide mononucleotide deaminase, nicotinamide nucleoside amidase, Nm deamidase, NMN deamidase, NMN deaminase, OiPncC, PncC, TK1650, YgaD

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.42 nicotinamide-nucleotide amidase

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Results	in table
3	Activating Compound
2395	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
2	Crystallization (Commentary)
2	Disease/ Diagnostics
21	General Information
2	General Stability
15	Inhibitors
10	kcat/KM [mM/s]
7	Ki Value [mM]
20	KM Value [mM]
1	Localization
2	Metals/Ions
9	Molecular Weight [Da]
34	Natural Substrates/ Products (Substrates)
36	Organism
5	Pathway
8	pH Optimum
4	pH Range
5	pH Stability
29	Protein Variants
10	Purification (Commentary)
5	Reaction
1	Reaction Type
36	Reference
20	Source Tissue
6	Specific Activity [micromol/min/mg]
3	Storage Stability
53	Substrates and Products (Substrate)
12	Subunits
41	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
12	Turnover Number [1/s]

pH Stability

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pH Stability on EC 3.5.1.42 - nicotinamide-nucleotide amidase

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pH STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

10

2 entries

3.8

Propionibacterium freudenreichii subsp. shermanii

-

21% retaining activity

209139

5 - 6

Aspergillus niger

-

stable within for 30 min

209134

7.4

Propionibacterium freudenreichii subsp. shermanii

-

48% retaining activity

209139

10

Oceanobacillus iheyensis

Q8EQR8

purified recombinant enzyme, 37°C, maintains 61% activity after 21 days

735110

10

Propionibacterium freudenreichii subsp. shermanii

-

25% retaining activity

209139