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3.5.1.42: nicotinamide-nucleotide amidase

This is an abbreviated version!
For detailed information about nicotinamide-nucleotide amidase, go to the full flat file.

Word Map on EC 3.5.1.42

Reaction

beta-nicotinamide D-ribonucleotide
+
H2O
=
beta-nicotinate D-ribonucleotide
+
NH3

Synonyms

AtCinA, CinA, nicotinamide mononucleotide amidohydrolase, nicotinamide mononucleotide deamidase, nicotinamide mononucleotide deaminase, nicotinamide nucleoside amidase, Nm deamidase, NMN deamidase, NMN deaminase, OiPncC, PncC, TK1650, YgaD

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.42 nicotinamide-nucleotide amidase

Reference

Reference on EC 3.5.1.42 - nicotinamide-nucleotide amidase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Foster, J.W.
Pyridine nucleotide cycle of Salmonella typhimurium: in vitro demonstration of nicotinamide adenine dinucleotide glycohydrolase, nicotinamide mononucleotide glycohydrolase, and nicotinamide adenine dinucleotide pyrophosphatase activities
J. Bacteriol.
145
1002-1009
1981
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Cheng, W.; Roth, J.
Isolation of NAD cycle mutants defective in nicotinamide mononucleotide deamidase in Salmonella typhimurium
J. Bacteriol.
177
6711-6717
1995
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Kuwahara, M.; Ishida, Y.; Okatani, M.
Nicotinamide nucleoside amidase activity, a novel deamidating reaction in NAD metabolism, in Aspergillus fungi
J. Ferment. Technol.
61
61-66
1983
Aspergillus awamori, Aspergillus flavus, Aspergillus niger, Aspergillus oryzae, Aspergillus usamii, Athelia rolfsii, Fusarium oxysporum, Trichoderma deliquescens, Rhizopus arrhizus
-
Manually annotated by BRENDA team
Foster, J.W.; Brestel, C.
NAD metabolism in Vibrio cholerae
J. Bacteriol.
149
368-371
1982
Vibrio cholerae serotype O1
Manually annotated by BRENDA team
Hillyard, D.; Rechsteiner, M.; Manlapaz-Ramos, P.; Imperial, J.S.; Cruz, L.J.; Olivera, B.M.
The pyridine nucleotide cycle. Studies in Escherichia coli and the human cell line D98/AH2
J. Biol. Chem.
256
8491-8497
1981
Escherichia coli, Homo sapiens
Manually annotated by BRENDA team
Kinney, D.M.; Foster, J.W.; Moat, A.G.
Pyridine nucleotide cycle of Samonella typhimurium: In vitro demonstration of nicotinamide mononucleotide deamidase and characterization of pnuA mutants defective in nicotinamide mononucleotide transport
J. Bacteriol.
140
607-611
1979
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Friedmann, H.C.; Garstki, C.
The pyridine nucleotide cycle: Presence of a nicotinamide mononucleotide-specific amidohydrolase in Propionibacterium shermanii
Biochem. Biophys. Res. Commun.
50
54-58
1973
Propionibacterium freudenreichii subsp. shermanii
Manually annotated by BRENDA team
Imai, T.
Purification and properties of nicotinamide mononucleotide amidohydrolase from Azotobacter vinelandii
J. Biochem.
73
139-153
1973
Azotobacter vinelandii, Escherichia coli, no activity in Saccharomyces cerevisiae, no activity in Oryctolagus cuniculus
Manually annotated by BRENDA team
Friedmann, H.C.
Preparation of nicotinic acid mononucleotide from nicotinamide mononucleotide by enzymatic deamidation
Methods Enzymol.
18
192-197
1971
Propionibacterium freudenreichii subsp. shermanii
-
Manually annotated by BRENDA team
Elzainy, T.A.; Ali, T.H.
NAD deamidation a new reaction by an enzyme from Aspergillus terreus DSM 826
Antonie van Leeuwenhoek
87
119-129
2005
Aspergillus terreus
Manually annotated by BRENDA team
Galeazzi, L.; Bocci, P.; Amici, A.; Brunetti, L.; Ruggieri, S.; Romine, M.; Reed, S.; Osterman, A.L.; Rodionov, D.A.; Sorci, L.; Raffaelli, N.
Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family
J. Biol. Chem.
286
40365-40375
2011
Escherichia coli, Shewanella oneidensis
Manually annotated by BRENDA team
Sorci, L.; Brunetti, L.; Cialabrini, L.; Mazzola, F.; Kazanov, M.D.; DAuria, S.; Ruggieri, S.; Raffaelli, N.
Characterization of bacterial NMN deamidase as a Ser/Lys hydrolase expands diversity of serine amidohydrolases
FEBS Lett.
588
1016-1023
2014
Escherichia coli
Manually annotated by BRENDA team
Karuppiah, V.; Thistlethwaite, A.; Dajani, R.; Warwicker, J.; Derrick, J.P.
Structure and mechanism of the bifunctional CinA enzyme from Thermus thermophilus
J. Biol. Chem.
289
33187-33197
2014
Thermus thermophilus (Q5SHB0), Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q5SHB0)
Manually annotated by BRENDA team
Sanchez-Carron, G.; Martinez-Monino, A.B.; Sola-Carvajal, A.; Takami, H.; Garcia-Carmona, F.; Sanchez-Ferrer, A.
New insights into the phylogeny and molecular classification of nicotinamide mononucleotide deamidases
PLoS ONE
8
e82705
2013
Oceanobacillus iheyensis (Q8EQR8), Oceanobacillus iheyensis, Oceanobacillus iheyensis HTE831 (Q8EQR8)
Manually annotated by BRENDA team
Di Stefano, M.; Loreto, A.; Orsomando, G.; Mori, V.; Zamporlini, F.; Hulse, R.P.; Webster, J.; Donaldson, L.F.; Gering, M.; Raffaelli, N.; Coleman, M.P.; Gilley, J.; Conforti, L.
NMN deamidase delays Wallerian degeneration and rescues axonal defects caused by NMNAT2 deficiency in vivo
Curr. Biol.
27
784-794
2017
Escherichia coli
Manually annotated by BRENDA team
Hachisuka, S.I.; Sato, T.; Atomi, H.
Hyperthermophilic archaeon Thermococcus kodakarensis utilizes a four-step pathway for NAD+ salvage through nicotinamide deamination
J. Bacteriol.
200
e00785-17
2018
Thermococcus kodakarensis (Q5JIT6), Thermococcus kodakarensis JCM 12380 (Q5JIT6), Thermococcus kodakarensis ATCC BAA-918 (Q5JIT6)
Manually annotated by BRENDA team
Martinez-Monino, A.B.; Zapata-Perez, R.; Garcia-Saura, A.G.; Gil-Ortiz, F.; Perez-Gilabert, M.; Sanchez-Ferrer, A.
Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency
PLoS ONE
12
e0174759
2017
Agrobacterium fabrum (A9CJ26), Agrobacterium fabrum C58 (A9CJ26), Agrobacterium fabrum ATCC 33970 (A9CJ26)
Manually annotated by BRENDA team