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3.5.1.42: nicotinamide-nucleotide amidase

This is an abbreviated version!
For detailed information about nicotinamide-nucleotide amidase, go to the full flat file.

Word Map on EC 3.5.1.42

Reaction

beta-nicotinamide D-ribonucleotide
+
H2O
=
beta-nicotinate D-ribonucleotide
+
NH3

Synonyms

AtCinA, CinA, nicotinamide mononucleotide amidohydrolase, nicotinamide mononucleotide deamidase, nicotinamide mononucleotide deaminase, nicotinamide nucleoside amidase, Nm deamidase, NMN deamidase, NMN deaminase, OiPncC, PncC, TK1650, YgaD

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.42 nicotinamide-nucleotide amidase

Natural Substrates Products

Natural Substrates Products on EC 3.5.1.42 - nicotinamide-nucleotide amidase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
beta-nicotinamide D-ribonucleotide + H2O
beta-nicotinate D-ribonucleotide + NH3
show the reaction diagram
nicotinamide mononucleotide + H2O
nicotinate mononucleotide + NH3
show the reaction diagram
nicotinamide ribonucleoside + H2O
nicotinic acid ribonucleoside + NH3
show the reaction diagram
additional information
?
-
-
the enzyme has no detectable deamidase activity toward NAD, NADP+, nicotinamide, and nicotinamide riboside
-
-
?