Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.5.1.42: nicotinamide-nucleotide amidase

This is an abbreviated version!
For detailed information about nicotinamide-nucleotide amidase, go to the full flat file.

Word Map on EC 3.5.1.42

Reaction

beta-nicotinamide D-ribonucleotide
+
H2O
=
beta-nicotinate D-ribonucleotide
 +
NH3

Synonyms

AtCinA, CinA, nicotinamide mononucleotide amidohydrolase, nicotinamide mononucleotide deamidase, nicotinamide mononucleotide deaminase, nicotinamide nucleoside amidase, Nm deamidase, NMN deamidase, NMN deaminase, OiPncC, PncC, TK1650, YgaD

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.42 nicotinamide-nucleotide amidase

Engineering

Engineering on EC 3.5.1.42 - nicotinamide-nucleotide amidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C32A
site-directed mutagenesis, the mutant shows 28% reduced activity compared to the wild-type enzyme
K638A
site-directed mutagenesis, inactive mutant
R145A
site-directed mutagenesis, inactive mutant
S31A
site-directed mutagenesis, inactive mutant
S48A
site-directed mutagenesis, the mutant shows 47% reduced activity compared to the wild-type enzyme
T105A
site-directed mutagenesis, the mutant shows 94% reduced activity compared to the wild-type enzyme
Y58A
site-directed mutagenesis, inactive mutant
Y58F
site-directed mutagenesis, almost inactive mutant
R145A
-
site-directed mutagenesis, inactive mutant
-
S31A
-
site-directed mutagenesis, inactive mutant
-
T105A
-
site-directed mutagenesis, the mutant shows 94% reduced activity compared to the wild-type enzyme
-
Y58A
-
site-directed mutagenesis, inactive mutant
-
Y58F
-
site-directed mutagenesis, almost inactive mutant
-
R145A
-
site-directed mutagenesis, inactive mutant
-
S31A
-
site-directed mutagenesis, inactive mutant
-
T105A
-
site-directed mutagenesis, the mutant shows 94% reduced activity compared to the wild-type enzyme
-
Y58A
-
site-directed mutagenesis, inactive mutant
-
Y58F
-
site-directed mutagenesis, almost inactive mutant
-
E28A
-
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
K61Q
-
site-directed mutagenesis, inactive mutant
R142A
-
site-directed mutagenesis, inactive mutant
S103A
-
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
S29A
-
site-directed mutagenesis, inactive mutant
T31A
-
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
Y56A
-
site-directed mutagenesis, inactive mutant
additional information