3.5.1.38: glutamin-(asparagin-)ase

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For detailed information about glutamin-(asparagin-)ase, go to the full flat file.

Word Map on EC 3.5.1.38

3.5.1.38

leukemia

lymphoblastic

l-asparaginase

succinylated

erwinia

6-diazo-5-oxo-l-norleucine

drug development

medicine

Reaction

Synonyms

asparaginase A, asparaginase B, glutaminase-asparaginase, glutaminase/asparaginase, periplasmic glutaminase/asparaginase, PGA

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.1.38 glutamin-(asparagin-)ase

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Results	in table
4	Activating Compound
288	AA Sequence
3	Application
1	CAS Registry Number
2	Cloned(Commentary)
4	Crystallization (Commentary)
2	General Stability
36	Inhibitors
3	Ki Value [mM]
25	KM Value [mM]
8	Localization
2	Metals/Ions
10	Molecular Weight [Da]
52	Natural Substrates/ Products (Substrates)
170	Organism
18	Pathway
34	PDB ID
4	pH Optimum
5	pH Range
3	pH Stability
2	Protein Variants
12	Purification (Commentary)
1	Reaction
1	Reaction Type
30	Reference
19	Source Tissue
13	Specific Activity [micromol/min/mg]
4	Storage Stability
117	Substrates and Products (Substrate)
13	Subunits
11	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
8	Temperature Stability [°C]
3	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.5.1.38 - glutamin-(asparagin-)ase

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1.6

asparaginase B

100

for L-asparagine

104

glutaminase activity

10510

Rhodotorula toruloides

asparaginase activity

209094

132.2

Streptomyces canarius

pH not specified in the publication, temperature not specified in the publication

753129

133

Citrobacter freundii

asparaginase A

209098

150

Acinetobacter glutaminasificans

209095

160

Pseudomonas sp.

209100

17.2

Tilachlidium humicola

209101

190

Achromobacter sp.

209103

2156

Rhodotorula toruloides

glutaminase activity

209094

Delftia acidovorans

asparaginase activity

209097

additional information

Pseudomonas putida

intracellular amino acid levels of wild-type and mutant strains

670274