3.5.1.3: omega-amidase
This is an abbreviated version!
For detailed information about omega-amidase, go to the full flat file.
Word Map on EC 3.5.1.3
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3.5.1.3
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alpha-ketoglutaramate
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asparagine
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transamination
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ammonia
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oxaloacetate
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succinamate
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glutaminase
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transamidase
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analysis
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medicine
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biotechnology
- 3.5.1.3
- alpha-ketoglutaramate
- asparagine
-
transamination
- ammonia
- oxaloacetate
- succinamate
- glutaminase
-
transamidase
- analysis
- medicine
- biotechnology
Reaction
Synonyms
alpha-keto acid omega-amidase, alpha-keto acid-omega-amidase, amidase, omega, dicarboxylate omega-amidase, NIT2, Nit2/omega-amidase, nitrilase-like protein 2, omega-amidase, omega-amidase/Nit2, omega-amido dicarboxylate amidohydrolase, omega-amidodicarboxylate amidohydrolase
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3.5.1.3 omega-amidaseAdvanced search results
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Natural Substrates Products on EC 3.5.1.3 - omega-amidase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
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alpha-ketoglutaramate
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?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
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physiological function of omega-amidase might be hydrolysis or transfer of amide group of alpha-ketoglutarate
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?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
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the in vivo substrates are generated by transamination of glutamine and asparagine, respectively
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-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
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alpha-ketoglutaramate
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?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
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alpha-ketoglutaramate
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?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
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alpha-ketoglutaramate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
alpha-ketoglutaramate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
alpha-ketoglutaramate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
alpha-ketoglutaramate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
alpha-ketoglutaramate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
alpha-ketoglutaramate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
alpha-ketoglutaramate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
the in vivo substrates are generated by transamination of glutamine and asparagine, respectively
-
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
alpha-ketoglutaramate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
alpha-ketoglutaramate
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?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
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glutamine transaminase and omega-amidase potentially act in tandem to close the methionine salvage cycle in bacteria and plants
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-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
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alpha-ketoglutaramate
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?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
-
physiological function of omega-amidase might be hydrolysis or transfer of amide group of alpha-ketoglutarate
-
?
2-oxoglutaramate + H2O
2-oxoglutarate + NH3
glutamine transaminase and omega-amidase potentially act in tandem to close the methionine salvage cycle in bacteria and plants
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-
?
2-oxosuccinamate + H2O
oxaloacetate + NH3
the product of asparagine transamination, 2-oxosuccinamate, can be hydrolyzed by the enzyme omega-amidase to form oxaloacetate and ammonia
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-
?
2-oxosuccinamate + H2O
oxaloacetate + NH3
the product of asparagine transamination, 2-oxosuccinamate, can be hydrolyzed by the enzyme omega-amidase to form oxaloacetate and ammonia
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-
?
2-oxosuccinamate + H2O
oxaloacetate + NH3
-
the in vivo substrates are generated by transamination of glutamine and asparagine, respectively
-
-
?
2-oxosuccinamate + H2O
oxaloacetate + NH3
-
the in vivo substrates are generated by transamination of glutamine and asparagine, respectively
-
-
?
additional information
?
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second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
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-
?
additional information
?
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enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine
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-
?
additional information
?
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enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine
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-
?
additional information
?
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-
enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine
-
-
?
additional information
?
-
-
second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
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-
?
additional information
?
-
-
second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
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-
?
additional information
?
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pathway for brain glutamine metabolism involves glutamine transaminase-omega-maidase pathway, L-glutamine: 2-oxo-acid amino-transferase, EC 2.6.1.15 and omega-amidodicarboxylate amidohydrolase, EC 3.5.1.3
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-
?
additional information
?
-
-
second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
-
-
?
additional information
?
-
-
second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
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-
?
additional information
?
-
-
enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine
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-
?
additional information
?
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conversion of glutamine into alpha-ketoglutarate and ammonia is brought about by two distinct enzymes: glutamine transaminase and omega-amidase
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-
?
additional information
?
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enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine
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-
?
additional information
?
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enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine
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-
?
additional information
?
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-
enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine
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-
?
additional information
?
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-
enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine
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-
?
additional information
?
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enzyme, in conjunction with glutamine transaminase comprises enzyme system previously designated glutaminase II, involved in metabolism of glutamine
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-
?
additional information
?
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second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
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-
?
additional information
?
-
-
second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
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-
?
additional information
?
-
-
second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
-
-
?
additional information
?
-
-
second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway
-
-
?
additional information
?
-
-
pathway for brain glutamine metabolism involves glutamine transaminase-omega-maidase pathway, L-glutamine: 2-oxo-acid amino-transferase, EC 2.6.1.15 and omega-amidodicarboxylate amidohydrolase, EC 3.5.1.3
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-
?
additional information
?
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high concentrations of omega-amidase in choroid plexus and in the S1-S3 region of nephron suggest that the glutaminase II pathway may generate appreciable ammonia locally in these organs, perhaps in association with transport
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?
additional information
?
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glutamine-transaminase-omega-amidase pathway, metabolic role: utilization of glutamine, formation of ammonia, ammoniagenesis, and utilization of certain alpha-keto acids for synthesis of corresponding amino acids
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-
?
