Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.5.1.24: choloylglycine hydrolase

This is an abbreviated version!
For detailed information about choloylglycine hydrolase, go to the full flat file.

Word Map on EC 3.5.1.24

Reaction

glycocholate
+
H2O
=
cholate
 +
glycine

Synonyms

BAH1, BFS26_06805, bile acid hydrolase, bile salt hydrolase, Bile-Salt-Hydrolase, BSH, BSH A, BSH B, BSH C, BSH1, BSH12, BSH2, BSH3, BSH4, BSH47, BSH56, BSHA, BSHB, BSHC, BT2086, C3745_01535, CBAH, CBH, CBSHalpha, CBSHbeta, CGH, cholylglycine hydrolase, Conjugated bile acid hydrolase, conjugated bile salt hydrolase, conjugated bile salt hydrolase alpha peptide, conjugated bile salt hydrolase beta, EFBG_01849, EfBSH, glycocholase, LaciP, LgBSH, linear amide C-N hydrolase, LJ1412, LJ_0056, LJ_1147, LsalN1, lsBSH, More, probiotic bile salt hydrolase, salt hydrolase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.24 choloylglycine hydrolase

Activating Compound

Activating Compound on EC 3.5.1.24 - choloylglycine hydrolase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
acetone
slight activation
FeSO4
-
114.7% residual activity
MgCl2
107.6% activity at 30 mM
MgSO4
112.6% activity at 30 mM
penicilin V
Pen V, is expected to cause competitive inhibition of BSH activity, but EfBSH shows enhanced activity towards glycodeoxycholic acid in the presence of Pen V, and no inhibition is observed, contrary to the expected results
Triton X-100
additional information
no effect on enzyme activity by EDTA
-