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BRENDA support

3.5.1.2: glutaminase

This is an abbreviated version!
For detailed information about glutaminase, go to the full flat file.

Word Map on EC 3.5.1.2

Reaction

L-glutamine
+
H2O
=
L-glutamate
+
NH3

Synonyms

AnsB, AoGls, GA, GAB, GAC, GahB, GLA, GLNase, GLS, GLS1, GLS2, GlsA, glutaminase, glutaminase 1, glutaminase 2, glutaminase A, glutaminase B, glutaminase C, glutaminase I, glutaminase K, glutaminase L, glutaminase-1, glutaminase-2, glutaminase-B, glutamine amidohydrolase, glutamine aminohydrolase, glutamine deamidating enzyme, K-glutaminase, KAG, KGA, kidney-type glutaminase, kidney-type-glutaminase, L-glutaminase, L-glutamine amidohydrolase, LAG, LGA, liver-type glitaminase, liver-type glutaminase, Mglu, Micrococcus glutaminase Mglu, Micrococcus luteus K-3-type glutaminase, mitochondrial glutaminase, N-PAG, neuroblastoma glutaminase, neuroblastoma PAG, Nit 2, nitrilase 2, omega-amidase, PAG, PDX2, phosphate activated glutaminase, phosphate-activated glutaminase, phosphate-activated L-glutamine amidohydrolase, salt-tolerant glutaminase, YaaE

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.2 glutaminase

Source Tissue

Source Tissue on EC 3.5.1.2 - glutaminase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
of medullar blood of acute lymphoblastic leukaemia patients
Manually annotated by BRENDA team
-
lymphoblastoid cell
Manually annotated by BRENDA team
-
isozymes LGA and KGA
Manually annotated by BRENDA team
-
splicing variant isozyme GAC
Manually annotated by BRENDA team
-
optimizing concentration of sucrose, yeast extract, glutamine, and sodium chloride for L-glutaminase production by response surface methodology
Manually annotated by BRENDA team
-
kidney-type glutaminase GLS1
Manually annotated by BRENDA team
-
phosphate-activated isozyme, mucosa
Manually annotated by BRENDA team
-
phosphate-activated isozyme
Manually annotated by BRENDA team
-
phosphate-activated isozyme
Manually annotated by BRENDA team
-
phosphate-activated isozyme
Manually annotated by BRENDA team
-
activity is enhanced following portacaval anastomosis
Manually annotated by BRENDA team
-
myeloid cell line
Manually annotated by BRENDA team
-
isozyme KGA
Manually annotated by BRENDA team
-
kidney-type glutaminase GLS1
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
-
duodenal
Manually annotated by BRENDA team
Triticale sp.
-
-
Manually annotated by BRENDA team
-
neuroblastoma cells, N-PAG, the proliferation state of the cells influence the specific activity. It is maximal at the start of the exponential phase of growth and is gradually reduced to a lower but significant level when the cell culture ceases to divide
Manually annotated by BRENDA team
-
kidney-type glutaminase GLS1
Manually annotated by BRENDA team
-
low expression level of isozymes LGA and KGA
Manually annotated by BRENDA team
-
isozyme K-PAG
Manually annotated by BRENDA team
-
breast cancer cell line
Manually annotated by BRENDA team
additional information