3.5.1.19: nicotinamidase

This is an abbreviated version!
For detailed information about nicotinamidase, go to the full flat file.

Reaction

Synonyms

AS87_01735, ASAC_0847, NAAA, NA_As0847, NIC, nicotinamidase, nicotinamidase PNC-1, nicotinamidase Pnc1p, nicotinamidase PncA, nicotinamidase/pyrazinamidase, nicotinamidase/pyrazinamidase PncA, nicotinamide amidase, nicotinamide deaminase, Nicotine deamidase, OiNIC, PNC-1, Pnc1, Pnc1p, PNC2, PncA, polygenomic nicotinamidase, PolyNic, pyrazinamidase, PZAase, PZAse, SpNic, TTHA0328, UbNic, YNDase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.19 nicotinamidase

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Results	in table
10	Activating Compound
4445	AA Sequence
7	Application
1	CAS Registry Number
28	Cloned(Commentary)
7	Crystallization (Commentary)
39	General Information
4	General Stability
150	Inhibitors
79	kcat/KM [mM/s]
45	Ki Value [mM]
97	KM Value [mM]
14	Localization
30	Metals/Ions
29	Molecular Weight [Da]
96	Natural Substrates/ Products (Substrates)
281	Organism
1	Oxidation Stability
8	Pathway
36	PDB ID
25	pH Optimum
10	pH Range
5	pH Stability
1	Posttranslational Modification
48	Protein Variants
29	Purification (Commentary)
3	Reaction
1	Reaction Type
76	Reference
19	Source Tissue
42	Specific Activity [micromol/min/mg]
4	Storage Stability
185	Substrates and Products (Substrate)
31	Subunits
69	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
9	Temperature Range [°C]
23	Temperature Stability [°C]
85	Turnover Number [1/s]

Organism

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Organism on EC 3.5.1.19 - nicotinamidase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Acidilobus saccharovorans

-

727053, 729184

D9Q1R5

UniProt

brenda

Acidilobus saccharovorans DSM 16705

-

727053, 729184

D9Q1R5

UniProt

brenda

Acinetobacter baumannii

2 entries

Alcaligenes sp. P156

-

755521

-

-

brenda

Arabidopsis thaliana

-

682376, 682380

-

-

brenda

Aspergillus niger

-

246567

-

-

brenda

Bacillus velezensis

-

752683

A0A223CGG0

UniProt

brenda

Borreliella burgdorferi

-

718859

-

-

brenda

Brucella abortus

gene pncA, a facultative intracellular pathogen

668655

-

-

brenda

Brucella abortus 544 / ATCC 23448

gene pncA, a facultative intracellular pathogen

668655

-

-

brenda

Caenorhabditis elegans

-

681746, 711827, 718859

-

-

brenda

Drosophila melanogaster

-

697513, 698815

-

-

brenda

Escherichia coli

2 entries

Flavobacterium peregrinum

-

246571, 246578

-

-

brenda

Leishmania infantum

-

719619, 720499

-

-

brenda

Leishmania infantum MHOM/MA/67/ITMAP-263

-

720499

-

-

brenda

Lotus japonicus

-

700669

-

-

brenda

Micrococcus luteus

i.e. Micrococcus lysodeiktikus

246573, 246574

-

-

brenda

Mus musculus

-

246576

-

-

brenda

Mycobacterium kansasii

-

246583, 246587

-

-

brenda

Mycobacterium tuberculosis

2 entries

Mycobacterium tuberculosis H37Rv

2 entries

Mycobacterium tuberculosis variant bovis

-

246587

-

-

brenda

Mycolicibacterium fortuitum

-

246587

-

-

brenda

Mycolicibacterium phlei

-

246587

-

-

brenda

Mycolicibacterium smegmatis

-

246584, 246585

-

-

brenda

no activity in Homo sapiens

-

753679

-

-

brenda

Oceanobacillus iheyensis

deep-sea extremely halotolerant and alkaliphilic organism

735084

Q8ESQ6

UniProt

brenda

Oceanobacillus iheyensis HTE831

deep-sea extremely halotolerant and alkaliphilic organism

735084

Q8ESQ6

UniProt

brenda

Oryctolagus cuniculus

-

246568, 246570, 246572

-

-

brenda

Plasmodium falciparum

-

246586, 718859

-

-

brenda

Pseudomonas sp.

-

246588

-

-

brenda

Pseudomonas sp. GDI 211

-

246588

-

-

brenda

Rattus norvegicus

-

1627, 246568

-

-

brenda

Riemerella anatipestifer

-

752546

-

-

brenda

Riemerella anatipestifer Yb2

-

752546

-

-

brenda

Saccharomyces cerevisiae

5 entries

Salmonella enterica subsp. enterica serovar Typhimurium

-

246575

-

-

brenda

Streptococcus pneumoniae

4 entries

Thermus thermophilus

-

754017

Q5SLG5

UniProt

brenda

uncultured Acidobacteria bacterium

nicotinamidase obtained from a metagenomic library fosmid clone (JFF054_F02) obtained from a geothermal water stream microbial mat community in a Japanese epithermal mine

755150

H5SPS2

UniProt

brenda

uncultured bacterium

mesophilic bacteria (MB) isolated from deep-sea hydrothermal vents sampled at various sites in Mid Atlantic Ridge

753679

-

-

brenda

unidentified

marine metagenome

753679

-

-

brenda

Vibrio cholerae serotype O1

strain CA401, strain FA18, strain FA64, strain FA86, strain FA131, strain 569B

209135

-

-

brenda

Vigna radiata var. radiata

-

659608

-

-

brenda

Acinetobacter baumannii

-

710862

-

-

brenda

Acinetobacter baumannii

gene pncA

735054

B0VA03

UniProt

brenda

Escherichia coli

-

246582

-

-

brenda

Escherichia coli

K12

246569

-

-

brenda

Mycobacterium tuberculosis

-

246585, 246587, 679806, 718885

-

-

brenda

Mycobacterium tuberculosis

gene pncA

735324

I6XD65

UniProt

brenda

Mycobacterium tuberculosis H37Rv

-

718885

-

-

brenda

Mycobacterium tuberculosis H37Rv

gene pncA

735324

I6XD65

UniProt

brenda

Saccharomyces cerevisiae

-

246577, 246581

-

-

brenda

Saccharomyces cerevisiae

-

677824

P53184

Uniprot

brenda

Saccharomyces cerevisiae

-

698121, 718859

-

-

brenda

Saccharomyces cerevisiae

-

718924

P53184

Uniprot

brenda

Saccharomyces cerevisiae

gene PNC1

670237

-

-

brenda

Streptococcus pneumoniae

-

718859

-

-

brenda

Streptococcus pneumoniae

-

718883

A0A0H2UR34

UniProt

brenda

Streptococcus pneumoniae

-

734741

-

-

brenda

Streptococcus pneumoniae

-

735054

A0A0H2UR34

UniProt

brenda